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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TSKS
Full Name:
Testis-specific serine kinase substrate
Alias:
STK22 substrate 1; Testis-specific kinase substrate; TSSKS
Type:
Kinase (non-protein)
Mass (Da):
65032
Number AA:
592
UniProt ID:
Q9UJT2
International Prot ID:
IPI00028056
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T21
E
I
H
E
A
G
D
T
P
T
G
V
E
S
C
Site 2
T23
H
E
A
G
D
T
P
T
G
V
E
S
C
S
Q
Site 3
S29
P
T
G
V
E
S
C
S
Q
L
V
P
E
A
P
Site 4
T40
P
E
A
P
R
R
V
T
S
R
A
K
G
I
P
Site 5
S41
E
A
P
R
R
V
T
S
R
A
K
G
I
P
K
Site 6
S54
P
K
K
K
K
A
V
S
F
H
G
V
E
P
Q
Site 7
S95
A
A
M
E
P
T
D
S
T
G
T
D
S
T
V
Site 8
T96
A
M
E
P
T
D
S
T
G
T
D
S
T
V
E
Site 9
S100
T
D
S
T
G
T
D
S
T
V
E
D
L
S
G
Site 10
T101
D
S
T
G
T
D
S
T
V
E
D
L
S
G
Q
Site 11
S106
D
S
T
V
E
D
L
S
G
Q
L
T
L
A
G
Site 12
T110
E
D
L
S
G
Q
L
T
L
A
G
P
P
A
S
Site 13
S117
T
L
A
G
P
P
A
S
P
T
L
P
W
D
P
Site 14
T119
A
G
P
P
A
S
P
T
L
P
W
D
P
D
D
Site 15
T130
D
P
D
D
A
D
I
T
E
I
L
S
G
V
N
Site 16
S138
E
I
L
S
G
V
N
S
G
L
V
R
A
K
D
Site 17
S146
G
L
V
R
A
K
D
S
I
T
S
L
K
E
K
Site 18
T154
I
T
S
L
K
E
K
T
N
R
V
N
Q
H
V
Site 19
S163
R
V
N
Q
H
V
Q
S
L
Q
S
E
C
S
V
Site 20
S166
Q
H
V
Q
S
L
Q
S
E
C
S
V
L
S
E
Site 21
S169
Q
S
L
Q
S
E
C
S
V
L
S
E
N
L
E
Site 22
Y188
E
A
E
E
L
E
G
Y
C
I
Q
L
K
E
N
Site 23
Y226
L
L
E
E
K
L
R
Y
L
Q
Q
Q
L
Q
D
Site 24
T235
Q
Q
Q
L
Q
D
E
T
P
R
R
Q
E
A
E
Site 25
S269
Q
K
P
E
A
G
L
S
W
N
S
L
G
P
A
Site 26
S272
E
A
G
L
S
W
N
S
L
G
P
A
A
T
S
Site 27
S279
S
L
G
P
A
A
T
S
Q
G
C
P
G
P
P
Site 28
S288
G
C
P
G
P
P
G
S
P
D
K
P
S
R
P
Site 29
S293
P
G
S
P
D
K
P
S
R
P
H
G
L
V
P
Site 30
Y314
P
R
A
G
E
G
P
Y
V
S
E
Q
E
L
Q
Site 31
S335
E
E
L
R
R
E
V
S
S
L
T
A
R
W
H
Site 32
S336
E
L
R
R
E
V
S
S
L
T
A
R
W
H
Q
Site 33
T338
R
R
E
V
S
S
L
T
A
R
W
H
Q
E
E
Site 34
T379
A
Q
R
E
Q
A
Q
T
A
R
D
L
Q
E
L
Site 35
S403
M
V
E
R
S
A
V
S
V
A
S
L
R
S
E
Site 36
S406
R
S
A
V
S
V
A
S
L
R
S
E
L
E
G
Site 37
S431
F
G
R
Q
F
Q
N
S
R
R
G
P
D
L
S
Site 38
S438
S
R
R
G
P
D
L
S
M
N
L
D
R
S
H
Site 39
S444
L
S
M
N
L
D
R
S
H
Q
G
N
C
A
R
Site 40
S454
G
N
C
A
R
C
A
S
Q
G
S
Q
L
S
T
Site 41
S457
A
R
C
A
S
Q
G
S
Q
L
S
T
E
S
L
Site 42
S460
A
S
Q
G
S
Q
L
S
T
E
S
L
Q
Q
L
Site 43
T461
S
Q
G
S
Q
L
S
T
E
S
L
Q
Q
L
L
Site 44
S463
G
S
Q
L
S
T
E
S
L
Q
Q
L
L
D
R
Site 45
T485
E
V
K
Q
R
G
L
T
P
A
C
P
S
C
Q
Site 46
S516
H
V
R
A
E
A
L
S
S
T
L
R
L
A
Q
Site 47
S517
V
R
A
E
A
L
S
S
T
L
R
L
A
Q
D
Site 48
T518
R
A
E
A
L
S
S
T
L
R
L
A
Q
D
E
Site 49
T535
R
A
K
N
L
L
L
T
D
K
M
K
P
E
E
Site 50
T546
K
P
E
E
K
M
A
T
L
D
H
L
H
L
K
Site 51
S562
C
S
L
H
D
H
L
S
N
L
P
L
E
G
S
Site 52
S569
S
N
L
P
L
E
G
S
T
G
T
M
G
G
G
Site 53
S577
T
G
T
M
G
G
G
S
S
A
G
T
P
P
K
Site 54
S578
G
T
M
G
G
G
S
S
A
G
T
P
P
K
Q
Site 55
T581
G
G
G
S
S
A
G
T
P
P
K
Q
G
G
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation