PhosphoNET

           
Protein Info 
   
Short Name:  HSPB8
Full Name:  Protein kinase H11 (putative)
Alias:  Alpha crystallin C chain; CRYAC; E2IG1; E2-induced gene 1 protein; HSP22
Type:  Protein-serine kinase, Atypical group, H11 family
Mass (Da):  21604
Number AA:  196
UniProt ID:  Q9UJY1
International Prot ID:  IPI00007264
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005622     Uniprot OncoNet
Molecular Function:  GO:0042802  GO:0004674   PhosphoSite+ KinaseNET
Biological Process:  GO:0008219  GO:0009408   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S9ADGQMPFSCHYPSRL
Site 2Y12QMPFSCHYPSRLRRD
Site 3S14PFSCHYPSRLRRDPF
Site 4S24RRDPFRDSPLSSRLL
Site 5S27PFRDSPLSSRLLDDG
Site 6S28FRDSPLSSRLLDDGF
Site 7T45DPFPDDLTASWPDWA
Site 8S47FPDDLTASWPDWALP
Site 9S57DWALPRLSSAWPGTL
Site 10S58WALPRLSSAWPGTLR
Site 11T63LSSAWPGTLRSGMVP
Site 12S66AWPGTLRSGMVPRGP
Site 13T87GVPAEGRTPPPFPGE
Site 14S104KVCVNVHSFKPEELM
Site 15Y118MVKTKDGYVEVSGKH
Site 16T140GIVSKNFTKKIQLPA
Site 17Y174EAPQVPPYSTFGESS
Site 18S175APQVPPYSTFGESSF
Site 19T176PQVPPYSTFGESSFN
Site 20S180PYSTFGESSFNNELP
Site 21S181YSTFGESSFNNELPQ
Site 22S190NNELPQDSQEVTCT_
Site 23T196DSQEVTCT_______
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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