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Updated November 2019
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Protein Info
Short Name:
ZC3H4
Full Name:
ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN C19ORF7.
Alias:
C19orf7; CS007; KIAA1064; LOC23211; Zinc finger CCCH domain-containing C19orf7; Zinc finger CCCH-type containing 4
Type:
Unknown function
Mass (Da):
140257
Number AA:
1303
UniProt ID:
Q9UPT8
International Prot ID:
IPI00187011
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0008270
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
E
A
A
P
G
T
P
P
P
P
P
S
E
Site 2
S13
G
T
P
P
P
P
P
S
E
S
P
P
P
P
S
Site 3
S15
P
P
P
P
P
S
E
S
P
P
P
P
S
P
P
Site 4
S20
S
E
S
P
P
P
P
S
P
P
P
P
S
T
P
Site 5
S25
P
P
S
P
P
P
P
S
T
P
S
P
P
P
C
Site 6
T26
P
S
P
P
P
P
S
T
P
S
P
P
P
C
S
Site 7
S28
P
P
P
P
S
T
P
S
P
P
P
C
S
P
D
Site 8
S33
T
P
S
P
P
P
C
S
P
D
A
R
P
A
T
Site 9
T40
S
P
D
A
R
P
A
T
P
H
L
L
H
H
R
Site 10
T72
E
D
D
G
A
E
E
T
Q
D
T
S
G
G
P
Site 11
T75
G
A
E
E
T
Q
D
T
S
G
G
P
E
R
S
Site 12
S76
A
E
E
T
Q
D
T
S
G
G
P
E
R
S
R
Site 13
S92
E
K
G
E
K
H
H
S
D
S
D
E
E
K
S
Site 14
S94
G
E
K
H
H
S
D
S
D
E
E
K
S
H
R
Site 15
S99
S
D
S
D
E
E
K
S
H
R
R
L
K
R
K
Site 16
S118
R
E
K
E
K
R
R
S
K
K
R
R
K
S
K
Site 17
S124
R
S
K
K
R
R
K
S
K
H
K
R
H
A
S
Site 18
S131
S
K
H
K
R
H
A
S
S
S
D
D
F
S
D
Site 19
S132
K
H
K
R
H
A
S
S
S
D
D
F
S
D
F
Site 20
S133
H
K
R
H
A
S
S
S
D
D
F
S
D
F
S
Site 21
S137
A
S
S
S
D
D
F
S
D
F
S
D
D
S
D
Site 22
S140
S
D
D
F
S
D
F
S
D
D
S
D
F
S
P
Site 23
S143
F
S
D
F
S
D
D
S
D
F
S
P
S
E
K
Site 24
S146
F
S
D
D
S
D
F
S
P
S
E
K
G
H
R
Site 25
S148
D
D
S
D
F
S
P
S
E
K
G
H
R
K
Y
Site 26
Y155
S
E
K
G
H
R
K
Y
R
E
Y
S
P
P
Y
Site 27
Y158
G
H
R
K
Y
R
E
Y
S
P
P
Y
A
P
S
Site 28
S159
H
R
K
Y
R
E
Y
S
P
P
Y
A
P
S
H
Site 29
Y162
Y
R
E
Y
S
P
P
Y
A
P
S
H
Q
Q
Y
Site 30
S165
Y
S
P
P
Y
A
P
S
H
Q
Q
Y
P
P
S
Site 31
Y169
Y
A
P
S
H
Q
Q
Y
P
P
S
H
A
T
P
Site 32
S172
S
H
Q
Q
Y
P
P
S
H
A
T
P
L
P
K
Site 33
T175
Q
Y
P
P
S
H
A
T
P
L
P
K
K
A
Y
Site 34
S183
P
L
P
K
K
A
Y
S
K
M
D
S
K
S
Y
Site 35
S187
K
A
Y
S
K
M
D
S
K
S
Y
G
M
Y
E
Site 36
Y193
D
S
K
S
Y
G
M
Y
E
D
Y
E
N
E
Q
Site 37
Y196
S
Y
G
M
Y
E
D
Y
E
N
E
Q
Y
G
E
Site 38
Y201
E
D
Y
E
N
E
Q
Y
G
E
Y
E
G
D
E
Site 39
Y204
E
N
E
Q
Y
G
E
Y
E
G
D
E
E
E
D
Site 40
Y217
E
D
M
G
K
E
D
Y
D
D
F
T
K
E
L
Site 41
T221
K
E
D
Y
D
D
F
T
K
E
L
N
Q
Y
R
Site 42
Y227
F
T
K
E
L
N
Q
Y
R
R
A
K
E
G
S
Site 43
S234
Y
R
R
A
K
E
G
S
S
R
G
R
G
S
R
Site 44
S235
R
R
A
K
E
G
S
S
R
G
R
G
S
R
G
Site 45
S240
G
S
S
R
G
R
G
S
R
G
R
G
R
G
Y
Site 46
Y247
S
R
G
R
G
R
G
Y
R
G
R
G
S
R
G
Site 47
S252
R
G
Y
R
G
R
G
S
R
G
G
S
R
G
R
Site 48
S256
G
R
G
S
R
G
G
S
R
G
R
G
M
G
R
Site 49
S265
G
R
G
M
G
R
G
S
R
G
R
G
R
G
S
Site 50
S272
S
R
G
R
G
R
G
S
M
G
G
D
H
P
E
Site 51
Y285
P
E
D
E
E
D
F
Y
E
E
E
M
D
Y
G
Site 52
Y291
F
Y
E
E
E
M
D
Y
G
E
S
E
E
P
M
Site 53
Y303
E
P
M
G
D
D
D
Y
D
E
Y
S
K
E
L
Site 54
Y306
G
D
D
D
Y
D
E
Y
S
K
E
L
N
Q
Y
Site 55
Y313
Y
S
K
E
L
N
Q
Y
R
R
S
K
D
S
R
Site 56
S316
E
L
N
Q
Y
R
R
S
K
D
S
R
G
R
G
Site 57
S319
Q
Y
R
R
S
K
D
S
R
G
R
G
L
S
R
Site 58
S325
D
S
R
G
R
G
L
S
R
G
R
G
R
G
S
Site 59
S332
S
R
G
R
G
R
G
S
R
G
R
G
K
G
M
Site 60
S348
R
G
R
G
R
G
G
S
R
G
G
M
N
K
G
Site 61
Y364
M
N
D
D
E
D
F
Y
D
E
D
M
G
D
G
Site 62
S375
M
G
D
G
G
G
G
S
Y
R
S
R
D
H
D
Site 63
Y376
M
N
D
D
E
D
F
Y
D
E
D
M
G
D
G
Site 64
S378
G
G
G
G
S
Y
R
S
R
D
H
D
K
P
H
Site 65
Y398
K
G
K
V
I
C
K
Y
F
V
E
G
R
C
T
Site 66
Y428
K
R
E
L
C
K
F
Y
I
T
G
F
C
A
R
Site 67
Y451
G
D
F
P
C
K
L
Y
H
T
T
G
N
C
I
Site 68
S466
N
G
D
D
C
M
F
S
H
D
P
L
T
E
E
Site 69
T471
M
F
S
H
D
P
L
T
E
E
T
R
E
L
L
Site 70
T519
P
G
V
G
L
L
P
T
P
P
R
P
P
G
P
Site 71
S531
P
G
P
Q
A
P
T
S
P
N
G
R
P
M
Q
Site 72
S566
M
P
V
H
E
P
L
S
P
Q
Q
L
Q
Q
Q
Site 73
Y576
Q
L
Q
Q
Q
D
M
Y
N
K
K
I
P
S
L
Site 74
Y674
G
G
P
P
M
M
P
Y
G
P
G
D
S
P
H
Site 75
S679
M
P
Y
G
P
G
D
S
P
H
S
G
M
M
P
Site 76
S682
G
P
G
D
S
P
H
S
G
M
M
P
P
I
P
Site 77
Y699
Q
N
F
Y
E
N
F
Y
Q
Q
Q
E
G
M
E
Site 78
Y718
L
L
G
D
A
E
D
Y
G
H
Y
E
E
L
P
Site 79
Y721
D
A
E
D
Y
G
H
Y
E
E
L
P
G
E
P
Site 80
S742
E
H
P
L
E
P
D
S
F
S
E
G
G
P
P
Site 81
S744
P
L
E
P
D
S
F
S
E
G
G
P
P
G
R
Site 82
Y770
P
S
A
Q
R
A
L
Y
L
R
I
Q
Q
K
Q
Site 83
S790
R
A
R
R
L
A
E
S
S
K
Q
D
R
E
N
Site 84
S791
A
R
R
L
A
E
S
S
K
Q
D
R
E
N
E
Site 85
T802
R
E
N
E
E
G
D
T
G
N
W
Y
S
S
D
Site 86
Y806
E
G
D
T
G
N
W
Y
S
S
D
E
D
E
G
Site 87
S807
G
D
T
G
N
W
Y
S
S
D
E
D
E
G
G
Site 88
S808
D
T
G
N
W
Y
S
S
D
E
D
E
G
G
S
Site 89
S815
S
D
E
D
E
G
G
S
S
V
T
S
I
L
K
Site 90
S816
D
E
D
E
G
G
S
S
V
T
S
I
L
K
T
Site 91
S819
E
G
G
S
S
V
T
S
I
L
K
T
L
R
Q
Site 92
T823
S
V
T
S
I
L
K
T
L
R
Q
Q
T
S
S
Site 93
T828
L
K
T
L
R
Q
Q
T
S
S
R
P
P
A
S
Site 94
S829
K
T
L
R
Q
Q
T
S
S
R
P
P
A
S
V
Site 95
S830
T
L
R
Q
Q
T
S
S
R
P
P
A
S
V
G
Site 96
S835
T
S
S
R
P
P
A
S
V
G
E
L
S
S
S
Site 97
S840
P
A
S
V
G
E
L
S
S
S
G
L
G
D
P
Site 98
S842
S
V
G
E
L
S
S
S
G
L
G
D
P
R
L
Site 99
S865
R
L
A
D
P
R
L
S
R
D
P
R
L
T
R
Site 100
T871
L
S
R
D
P
R
L
T
R
H
V
E
A
S
G
Site 101
S877
L
T
R
H
V
E
A
S
G
G
S
G
P
G
D
Site 102
S880
H
V
E
A
S
G
G
S
G
P
G
D
S
G
P
Site 103
S885
G
G
S
G
P
G
D
S
G
P
S
D
P
R
L
Site 104
S888
G
P
G
D
S
G
P
S
D
P
R
L
A
R
A
Site 105
T898
R
L
A
R
A
L
P
T
S
K
P
E
G
S
L
Site 106
S899
L
A
R
A
L
P
T
S
K
P
E
G
S
L
H
Site 107
S904
P
T
S
K
P
E
G
S
L
H
S
S
P
V
G
Site 108
S907
K
P
E
G
S
L
H
S
S
P
V
G
P
S
S
Site 109
S908
P
E
G
S
L
H
S
S
P
V
G
P
S
S
S
Site 110
S913
H
S
S
P
V
G
P
S
S
S
K
G
S
G
P
Site 111
S914
S
S
P
V
G
P
S
S
S
K
G
S
G
P
P
Site 112
S915
S
P
V
G
P
S
S
S
K
G
S
G
P
P
P
Site 113
S918
G
P
S
S
S
K
G
S
G
P
P
P
T
E
E
Site 114
T923
K
G
S
G
P
P
P
T
E
E
E
E
G
E
R
Site 115
S954
H
P
L
R
D
P
R
S
Q
L
Q
Q
F
S
H
Site 116
S960
R
S
Q
L
Q
Q
F
S
H
I
K
K
D
V
T
Site 117
T967
S
H
I
K
K
D
V
T
L
S
K
P
S
F
A
Site 118
S969
I
K
K
D
V
T
L
S
K
P
S
F
A
R
T
Site 119
T976
S
K
P
S
F
A
R
T
V
L
W
N
P
E
D
Site 120
S1004
P
V
P
A
A
L
Q
S
M
P
T
L
D
P
R
Site 121
T1007
A
A
L
Q
S
M
P
T
L
D
P
R
L
H
R
Site 122
T1017
P
R
L
H
R
A
A
T
A
G
P
P
N
A
R
Site 123
S1030
A
R
Q
R
P
G
A
S
T
D
S
S
T
Q
G
Site 124
T1031
R
Q
R
P
G
A
S
T
D
S
S
T
Q
G
A
Site 125
S1033
R
P
G
A
S
T
D
S
S
T
Q
G
A
N
L
Site 126
S1034
P
G
A
S
T
D
S
S
T
Q
G
A
N
L
P
Site 127
T1035
G
A
S
T
D
S
S
T
Q
G
A
N
L
P
D
Site 128
S1058
K
T
V
N
A
T
G
S
S
A
A
P
G
S
S
Site 129
S1059
T
V
N
A
T
G
S
S
A
A
P
G
S
S
D
Site 130
S1064
G
S
S
A
A
P
G
S
S
D
K
P
S
D
P
Site 131
S1065
S
S
A
A
P
G
S
S
D
K
P
S
D
P
R
Site 132
S1069
P
G
S
S
D
K
P
S
D
P
R
V
R
K
A
Site 133
T1086
D
P
R
L
Q
K
P
T
D
S
T
A
S
S
R
Site 134
S1088
R
L
Q
K
P
T
D
S
T
A
S
S
R
A
A
Site 135
S1091
K
P
T
D
S
T
A
S
S
R
A
A
K
P
G
Site 136
S1092
P
T
D
S
T
A
S
S
R
A
A
K
P
G
P
Site 137
S1104
P
G
P
A
E
A
P
S
P
T
A
S
P
S
G
Site 138
T1106
P
A
E
A
P
S
P
T
A
S
P
S
G
D
A
Site 139
S1108
E
A
P
S
P
T
A
S
P
S
G
D
A
S
P
Site 140
S1110
P
S
P
T
A
S
P
S
G
D
A
S
P
P
A
Site 141
S1114
A
S
P
S
G
D
A
S
P
P
A
T
A
P
Y
Site 142
T1118
G
D
A
S
P
P
A
T
A
P
Y
D
P
R
V
Site 143
Y1121
S
P
P
A
T
A
P
Y
D
P
R
V
L
A
A
Site 144
S1140
Q
G
G
G
G
G
Q
S
S
V
L
S
G
I
S
Site 145
S1144
G
G
Q
S
S
V
L
S
G
I
S
L
Y
D
P
Site 146
S1147
S
S
V
L
S
G
I
S
L
Y
D
P
R
T
P
Site 147
Y1149
V
L
S
G
I
S
L
Y
D
P
R
T
P
N
A
Site 148
T1153
I
S
L
Y
D
P
R
T
P
N
A
G
G
K
A
Site 149
T1161
P
N
A
G
G
K
A
T
E
P
A
A
D
T
G
Site 150
T1167
I
S
L
Y
D
P
R
T
P
N
A
G
G
K
A
Site 151
S1180
G
A
E
G
N
G
K
S
S
A
S
K
A
K
E
Site 152
S1181
A
E
G
N
G
K
S
S
A
S
K
A
K
E
P
Site 153
S1183
G
N
G
K
S
S
A
S
K
A
K
E
P
P
F
Site 154
S1194
E
P
P
F
V
R
K
S
A
L
E
Q
P
E
T
Site 155
T1201
S
A
L
E
Q
P
E
T
G
K
A
G
A
D
G
Site 156
T1210
K
A
G
A
D
G
G
T
P
T
D
R
Y
N
S
Site 157
T1212
G
A
D
G
G
T
P
T
D
R
Y
N
S
Y
N
Site 158
Y1215
G
G
T
P
T
D
R
Y
N
S
Y
N
R
P
R
Site 159
S1217
T
P
T
D
R
Y
N
S
Y
N
R
P
R
P
K
Site 160
Y1218
P
T
D
R
Y
N
S
Y
N
R
P
R
P
K
A
Site 161
T1235
A
P
A
A
T
T
A
T
P
P
P
E
G
A
P
Site 162
T1258
P
V
P
T
L
F
G
T
V
K
Q
T
P
K
T
Site 163
T1262
L
F
G
T
V
K
Q
T
P
K
T
G
S
G
S
Site 164
T1265
T
V
K
Q
T
P
K
T
G
S
G
S
P
F
A
Site 165
S1267
K
Q
T
P
K
T
G
S
G
S
P
F
A
G
N
Site 166
S1269
T
P
K
T
G
S
G
S
P
F
A
G
N
S
P
Site 167
S1275
G
S
P
F
A
G
N
S
P
A
R
E
G
E
Q
Site 168
S1286
E
G
E
Q
D
A
A
S
L
K
D
V
F
K
G
Site 169
T1297
V
F
K
G
F
D
P
T
A
S
P
F
C
Q
_
Site 170
S1299
K
G
F
D
P
T
A
S
P
F
C
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation