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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DRG1
Full Name:
Developmentally-regulated GTP-binding protein 1
Alias:
developmentally regulated GTP binding protein 1; developmentally-regulated GTP-binding 1; DKFZp434N1827; DRG 1; NEDD3; neural precursor cell expressed developmentally down-regulated 3
Type:
Transcription, coactivator/corepressor
Mass (Da):
40542
Number AA:
367
UniProt ID:
Q9Y295
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0005525
GO:0008134
PhosphoSite+
KinaseNET
Biological Process:
GO:0007275
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T44
K
L
R
R
E
L
I
T
P
K
G
G
G
G
G
Site 2
T62
E
G
F
D
V
A
K
T
G
D
A
R
I
G
F
Site 3
T101
Y
E
F
T
T
L
T
T
V
P
G
V
I
R
Y
Site 4
S174
G
F
G
I
R
L
N
S
K
P
P
N
I
G
F
Site 5
T194
G
G
I
N
L
T
A
T
C
P
Q
S
E
L
D
Site 6
S198
L
T
A
T
C
P
Q
S
E
L
D
A
E
T
V
Site 7
T204
Q
S
E
L
D
A
E
T
V
K
S
I
L
A
E
Site 8
T220
K
I
H
N
A
D
V
T
L
R
S
D
A
T
A
Site 9
Y240
V
V
E
G
N
R
V
Y
I
P
C
I
Y
V
L
Site 10
Y262
I
E
E
L
D
I
I
Y
K
V
P
H
C
V
P
Site 11
Y295
Y
L
K
L
V
R
I
Y
T
K
P
K
G
Q
L
Site 12
T296
L
K
L
V
R
I
Y
T
K
P
K
G
Q
L
P
Site 13
Y305
P
K
G
Q
L
P
D
Y
T
S
P
V
V
L
P
Site 14
T306
K
G
Q
L
P
D
Y
T
S
P
V
V
L
P
Y
Site 15
S307
G
Q
L
P
D
Y
T
S
P
V
V
L
P
Y
S
Site 16
S314
S
P
V
V
L
P
Y
S
R
T
T
V
E
D
F
Site 17
T317
V
L
P
Y
S
R
T
T
V
E
D
F
C
M
K
Site 18
T355
Q
K
V
G
K
D
H
T
L
E
D
E
D
V
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation