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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PRKAB1
Full Name:
5'-AMP-activated protein kinase subunit beta-1
Alias:
5'-AMP-activated protein kinase, beta-1 subunit; AAKB1; AMPK beta 1; AMPK beta-1 chain; AMPK-beta1; Kinase AMPK-beta1; Protein kinase, AMP-activated, beta 1 non-catalytic subunit
Type:
Protein-serine kinase, regulatory subunit
Mass (Da):
30382
Number AA:
270
UniProt ID:
Q9Y478
International Prot ID:
IPI00220409
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006633
GO:0046320
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T4
_
_
_
_
M
G
N
T
S
S
E
R
A
A
L
Site 2
S5
_
_
_
M
G
N
T
S
S
E
R
A
A
L
E
Site 3
S6
_
_
M
G
N
T
S
S
E
R
A
A
L
E
R
Site 4
T19
E
R
H
G
G
H
K
T
P
R
R
D
S
S
G
Site 5
S24
H
K
T
P
R
R
D
S
S
G
G
T
K
D
G
Site 6
S25
K
T
P
R
R
D
S
S
G
G
T
K
D
G
D
Site 7
T28
R
R
D
S
S
G
G
T
K
D
G
D
R
P
K
Site 8
S40
R
P
K
I
L
M
D
S
P
E
D
A
D
L
F
Site 9
T80
A
P
A
Q
A
R
P
T
V
F
R
W
T
G
G
Site 10
T85
R
P
T
V
F
R
W
T
G
G
G
K
E
V
Y
Site 11
Y92
T
G
G
G
K
E
V
Y
L
S
G
S
F
N
N
Site 12
S94
G
G
K
E
V
Y
L
S
G
S
F
N
N
W
S
Site 13
S96
K
E
V
Y
L
S
G
S
F
N
N
W
S
K
L
Site 14
S101
S
G
S
F
N
N
W
S
K
L
P
L
T
R
S
Site 15
T106
N
W
S
K
L
P
L
T
R
S
H
N
N
F
V
Site 16
S108
S
K
L
P
L
T
R
S
H
N
N
F
V
A
I
Site 17
S138
G
Q
W
T
H
D
P
S
E
P
I
V
T
S
Q
Site 18
T143
D
P
S
E
P
I
V
T
S
Q
L
G
T
V
N
Site 19
S144
P
S
E
P
I
V
T
S
Q
L
G
T
V
N
N
Site 20
T148
I
V
T
S
Q
L
G
T
V
N
N
I
I
Q
V
Site 21
T158
N
I
I
Q
V
K
K
T
D
F
E
V
F
D
A
Site 22
S170
F
D
A
L
M
V
D
S
Q
K
C
S
D
V
S
Site 23
S174
M
V
D
S
Q
K
C
S
D
V
S
E
L
S
S
Site 24
S177
S
Q
K
C
S
D
V
S
E
L
S
S
S
P
P
Site 25
S180
C
S
D
V
S
E
L
S
S
S
P
P
G
P
Y
Site 26
S181
S
D
V
S
E
L
S
S
S
P
P
G
P
Y
H
Site 27
S182
D
V
S
E
L
S
S
S
P
P
G
P
Y
H
Q
Site 28
Y187
S
S
S
P
P
G
P
Y
H
Q
E
P
Y
V
C
Site 29
Y192
G
P
Y
H
Q
E
P
Y
V
C
K
P
E
E
R
Site 30
Y240
H
V
M
L
N
H
L
Y
A
L
S
I
K
D
G
Site 31
S252
K
D
G
V
M
V
L
S
A
T
H
R
Y
K
K
Site 32
T254
G
V
M
V
L
S
A
T
H
R
Y
K
K
K
Y
Site 33
Y261
T
H
R
Y
K
K
K
Y
V
T
T
L
L
Y
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation