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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC12A8 All Species: 20.61
Human Site: S103 Identified Species: 45.33
UniProt: A0AV02 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A0AV02 NP_078904.3 714 78223 S103 G E R S S I G S G G V Y S M I
Chimpanzee Pan troglodytes XP_516709 941 101578 S330 G E R S S I G S G G V Y S M I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_545139 840 90619 S229 G E H C G V G S G G V Y S M I
Cat Felis silvestris
Mouse Mus musculus Q8VI23 705 77001 S102 A E H G G I S S G G V Y S M I
Rat Rattus norvegicus Q8CJI3 707 77054 S102 A E H G W M G S G G V Y S M I
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6A4L1 721 79387 S117 C E R C S I G S G G V Y S M V
Zebra Danio Brachydanio rerio A2BFP5 899 98457 G107 S T N G A V E G G G A Y F M I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_397130 677 75119 I98 F T S C L I N I F G V I V F L
Nematode Worm Caenorhab. elegans Q09573 1020 112280 S134 A T N G V V E S G G A Y F I I
Sea Urchin Strong. purpuratus XP_796834 688 74559 R98 W K A N F F V R E P V L F G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38329 1120 123980 G127 S T N G T V R G G G A Y Y M I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.4 N.A. 73.8 N.A. 79.5 77.8 N.A. N.A. N.A. 64.2 22.7 N.A. N.A. 41.7 21.8 43.7
Protein Similarity: 100 73.9 N.A. 78.4 N.A. 87.1 84.8 N.A. N.A. N.A. 76.4 41.1 N.A. N.A. 60.6 37.9 59.1
P-Site Identity: 100 100 N.A. 73.3 N.A. 66.6 66.6 N.A. N.A. N.A. 80 33.3 N.A. N.A. 20 33.3 6.6
P-Site Similarity: 100 100 N.A. 80 N.A. 66.6 73.3 N.A. N.A. N.A. 86.6 46.6 N.A. N.A. 26.6 46.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 20 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 35.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 28 0 10 0 10 0 0 0 0 0 28 0 0 0 0 % A
% Cys: 10 0 0 28 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 55 0 0 0 0 19 0 10 0 0 0 0 0 0 % E
% Phe: 10 0 0 0 10 10 0 0 10 0 0 0 28 10 0 % F
% Gly: 28 0 0 46 19 0 46 19 82 91 0 0 0 10 0 % G
% His: 0 0 28 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 46 0 10 0 0 0 10 0 10 73 % I
% Lys: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 10 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 73 0 % M
% Asn: 0 0 28 10 0 0 10 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 28 0 0 0 10 10 0 0 0 0 0 0 0 % R
% Ser: 19 0 10 19 28 0 10 64 0 0 0 0 55 0 0 % S
% Thr: 0 37 0 0 10 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 10 37 10 0 0 0 73 0 10 0 10 % V
% Trp: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 82 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _