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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A8
All Species:
22.73
Human Site:
S228
Identified Species:
50
UniProt:
A0AV02
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0AV02
NP_078904.3
714
78223
S228
N
N
T
L
P
D
Y
S
P
G
E
S
F
F
T
Chimpanzee
Pan troglodytes
XP_516709
941
101578
S455
N
N
S
Q
V
L
Y
S
P
G
T
S
G
F
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545139
840
90619
S354
N
N
T
L
P
D
Y
S
P
G
E
S
F
F
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI23
705
77001
S227
S
N
I
L
P
E
Y
S
P
G
E
S
F
F
T
Rat
Rattus norvegicus
Q8CJI3
707
77054
S227
S
N
I
L
P
E
Y
S
P
G
E
S
F
F
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6A4L1
721
79387
T242
N
N
T
F
P
D
Y
T
P
G
E
S
F
F
T
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
Y245
S
V
T
V
S
P
S
Y
T
G
F
N
S
T
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397130
677
75119
A206
A
W
A
E
R
G
F
A
C
A
A
V
I
L
L
Nematode Worm
Caenorhab. elegans
Q09573
1020
112280
V363
K
S
E
V
V
P
G
V
R
G
K
E
T
A
E
Sea Urchin
Strong. purpuratus
XP_796834
688
74559
T212
F
G
E
S
V
A
K
T
F
G
W
Q
N
A
W
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38329
1120
123980
K279
G
A
A
G
S
L
L
K
G
K
E
T
F
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.4
N.A.
73.8
N.A.
79.5
77.8
N.A.
N.A.
N.A.
64.2
22.7
N.A.
N.A.
41.7
21.8
43.7
Protein Similarity:
100
73.9
N.A.
78.4
N.A.
87.1
84.8
N.A.
N.A.
N.A.
76.4
41.1
N.A.
N.A.
60.6
37.9
59.1
P-Site Identity:
100
60
N.A.
100
N.A.
80
80
N.A.
N.A.
N.A.
86.6
20
N.A.
N.A.
0
6.6
6.6
P-Site Similarity:
100
66.6
N.A.
100
N.A.
93.3
93.3
N.A.
N.A.
N.A.
93.3
40
N.A.
N.A.
13.3
26.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
19
0
0
10
0
10
0
10
10
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
28
0
0
0
0
0
0
0
0
10
% D
% Glu:
0
0
19
10
0
19
0
0
0
0
55
10
0
0
10
% E
% Phe:
10
0
0
10
0
0
10
0
10
0
10
0
55
55
0
% F
% Gly:
10
10
0
10
0
10
10
0
10
82
0
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
19
0
0
0
0
0
0
0
0
0
10
0
0
% I
% Lys:
10
0
0
0
0
0
10
10
0
10
10
0
0
0
0
% K
% Leu:
0
0
0
37
0
19
10
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
37
55
0
0
0
0
0
0
0
0
0
10
10
10
0
% N
% Pro:
0
0
0
0
46
19
0
0
55
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% R
% Ser:
28
10
10
10
19
0
10
46
0
0
0
55
10
0
0
% S
% Thr:
0
0
37
0
0
0
0
19
10
0
10
10
10
10
64
% T
% Val:
0
10
0
19
28
0
0
10
0
0
0
10
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
10
0
0
0
10
% W
% Tyr:
0
0
0
0
0
0
55
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _