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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC12A8
All Species:
18.48
Human Site:
S635
Identified Species:
40.67
UniProt:
A0AV02
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0AV02
NP_078904.3
714
78223
S635
Y
F
Y
I
G
R
A
S
P
G
L
H
L
G
S
Chimpanzee
Pan troglodytes
XP_516709
941
101578
S862
Y
F
Y
I
G
R
A
S
P
G
L
H
L
G
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_545139
840
90619
S761
Y
F
Y
I
G
R
A
S
P
G
L
H
L
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VI23
705
77001
S626
Y
F
Y
I
G
Q
A
S
P
G
L
Y
L
G
S
Rat
Rattus norvegicus
Q8CJI3
707
77054
S627
Y
L
Y
I
G
Q
A
S
P
G
L
Y
L
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6A4L1
721
79387
N642
Y
L
Y
I
G
R
V
N
P
G
L
N
P
G
A
Zebra Danio
Brachydanio rerio
A2BFP5
899
98457
R710
G
K
N
I
C
L
A
R
Y
F
F
Q
L
P
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397130
677
75119
N593
W
S
Y
I
G
H
A
N
P
A
V
K
P
G
V
Nematode Worm
Caenorhab. elegans
Q09573
1020
112280
S821
S
E
Q
D
S
T
K
S
E
D
M
K
A
G
L
Sea Urchin
Strong. purpuratus
XP_796834
688
74559
L610
F
C
N
R
W
V
S
L
I
G
P
L
S
W
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38329
1120
123980
D752
G
K
V
E
A
K
G
D
Q
P
A
A
I
T
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
72.4
N.A.
73.8
N.A.
79.5
77.8
N.A.
N.A.
N.A.
64.2
22.7
N.A.
N.A.
41.7
21.8
43.7
Protein Similarity:
100
73.9
N.A.
78.4
N.A.
87.1
84.8
N.A.
N.A.
N.A.
76.4
41.1
N.A.
N.A.
60.6
37.9
59.1
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
N.A.
N.A.
60
20
N.A.
N.A.
40
13.3
6.6
P-Site Similarity:
100
100
N.A.
93.3
N.A.
100
93.3
N.A.
N.A.
N.A.
80
20
N.A.
N.A.
60
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
10
0
64
0
0
10
10
10
10
0
10
% A
% Cys:
0
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
10
0
10
0
0
0
0
0
% D
% Glu:
0
10
0
10
0
0
0
0
10
0
0
0
0
0
0
% E
% Phe:
10
37
0
0
0
0
0
0
0
10
10
0
0
0
0
% F
% Gly:
19
0
0
0
64
0
10
0
0
64
0
0
0
73
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
28
0
0
0
% H
% Ile:
0
0
0
73
0
0
0
0
10
0
0
0
10
0
0
% I
% Lys:
0
19
0
0
0
10
10
0
0
0
0
19
0
0
0
% K
% Leu:
0
19
0
0
0
10
0
10
0
0
55
10
55
0
19
% L
% Met:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% M
% Asn:
0
0
19
0
0
0
0
19
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
64
10
10
0
19
10
10
% P
% Gln:
0
0
10
0
0
19
0
0
10
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
0
37
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
10
0
0
10
0
10
55
0
0
0
0
10
0
37
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
10
% T
% Val:
0
0
10
0
0
10
10
0
0
0
10
0
0
0
10
% V
% Trp:
10
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
55
0
64
0
0
0
0
0
10
0
0
19
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _