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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM129
All Species:
26.06
Human Site:
S144
Identified Species:
63.7
UniProt:
A0AVI4
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0AVI4
NP_001120738.1
362
40464
S144
G
W
Q
A
V
A
S
S
V
N
T
E
F
R
R
Chimpanzee
Pan troglodytes
XP_517063
337
37545
I127
V
N
T
E
F
R
R
I
D
K
F
A
T
G
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850740
362
40319
S144
D
W
W
A
V
A
S
S
V
N
T
E
F
R
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K304
362
40609
S144
G
W
Q
A
V
A
S
S
I
N
T
E
F
R
R
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520916
507
55864
S289
G
W
Q
S
V
A
T
S
I
N
T
E
F
R
R
Chicken
Gallus gallus
Q5ZI25
362
40944
S144
G
W
R
A
V
A
S
S
I
N
T
E
F
R
R
Frog
Xenopus laevis
Q6IR55
362
40979
S144
S
W
R
A
V
A
S
S
I
N
T
E
F
R
R
Zebra Danio
Brachydanio rerio
Q6PD82
361
41127
S144
S
W
R
A
V
A
S
S
I
N
T
E
F
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395812
370
42655
I148
W
T
T
V
A
S
D
I
N
V
E
Y
Q
R
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790185
302
34589
K92
I
E
F
R
R
I
N
K
F
S
T
G
P
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
84.5
N.A.
91.1
N.A.
89.2
N.A.
N.A.
53.8
75.4
74.3
64.6
N.A.
N.A.
40
N.A.
39.5
Protein Similarity:
100
85.9
N.A.
95
N.A.
94.1
N.A.
N.A.
62.1
84.5
87
79
N.A.
N.A.
58.1
N.A.
55.8
P-Site Identity:
100
0
N.A.
86.6
N.A.
93.3
N.A.
N.A.
80
86.6
80
80
N.A.
N.A.
6.6
N.A.
6.6
P-Site Similarity:
100
0
N.A.
86.6
N.A.
100
N.A.
N.A.
100
100
93.3
93.3
N.A.
N.A.
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
60
10
70
0
0
0
0
0
10
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
10
0
0
0
0
0
0
% D
% Glu:
0
10
0
10
0
0
0
0
0
0
10
70
0
0
0
% E
% Phe:
0
0
10
0
10
0
0
0
10
0
10
0
70
0
0
% F
% Gly:
40
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
0
20
50
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
10
0
10
70
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% P
% Gln:
0
0
30
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
30
10
10
10
10
0
0
0
0
0
0
80
70
% R
% Ser:
20
0
0
10
0
10
60
70
0
10
0
0
0
0
10
% S
% Thr:
0
10
20
0
0
0
10
0
0
0
80
0
10
0
0
% T
% Val:
10
0
0
10
70
0
0
0
20
10
0
0
0
0
0
% V
% Trp:
10
70
10
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _