Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED19 All Species: 35.76
Human Site: S129 Identified Species: 60.51
UniProt: A0JLT2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A0JLT2 NP_703151.1 244 26273 S129 H D N S S L R S L I E K P P I
Chimpanzee Pan troglodytes XP_508439 244 26239 S129 H D N S S L R S L I E K P P I
Rhesus Macaque Macaca mulatta XP_001101030 244 26295 S129 H D N S S L R S L I E K P P I
Dog Lupus familis XP_852656 244 26173 S129 H D N S S L R S L I E K P P I
Cat Felis silvestris
Mouse Mus musculus Q8C1S0 244 26244 S129 H D N S S L R S L I E K P P I
Rat Rattus norvegicus NP_001101211 244 26303 S129 H D N S S L R S L I E K P P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513917 197 22078 E109 L H A G P L P E Q C R L M H I
Chicken Gallus gallus XP_426411 237 25493 S122 H D N S S L R S L I E K P P I
Frog Xenopus laevis Q5EAY2 240 26246 S129 P D N S S L R S L I E K P P I
Zebra Danio Brachydanio rerio Q6DRL8 240 26987 S126 Q D N S S L R S L I E K P P V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VVL6 337 35372 E128 K P P I G G K E L L P L T P V
Honey Bee Apis mellifera XP_395809 241 26966 P147 G F R L H P G P L P E Q Y R Y
Nematode Worm Caenorhab. elegans Q9N4F2 199 22779 K111 S S S M Q G F K L S A G P V D
Sea Urchin Strong. purpuratus XP_793184 239 26596 Q135 T F T T G M L Q G F K L H P G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 99.1 95 N.A. 94.2 94.6 N.A. 69.6 82.3 63.5 69.6 N.A. 31.7 47.9 25.4 42.6
Protein Similarity: 100 99.5 99.5 97.1 N.A. 95.9 96.3 N.A. 71.3 85.6 75 77.4 N.A. 42.1 62.7 40.9 59
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 93.3 86.6 N.A. 13.3 13.3 13.3 6.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 13.3 100 93.3 93.3 N.A. 33.3 20 20 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 0 0 0 0 0 0 0 8 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % C
% Asp: 0 65 0 0 0 0 0 0 0 0 0 0 0 0 8 % D
% Glu: 0 0 0 0 0 0 0 15 0 0 72 0 0 0 0 % E
% Phe: 0 15 0 0 0 0 8 0 0 8 0 0 0 0 0 % F
% Gly: 8 0 0 8 15 15 8 0 8 0 0 8 0 0 8 % G
% His: 50 8 0 0 8 0 0 0 0 0 0 0 8 8 0 % H
% Ile: 0 0 0 8 0 0 0 0 0 65 0 0 0 0 65 % I
% Lys: 8 0 0 0 0 0 8 8 0 0 8 65 0 0 0 % K
% Leu: 8 0 0 8 0 72 8 0 86 8 0 22 0 0 0 % L
% Met: 0 0 0 8 0 8 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 65 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 8 8 8 0 8 8 8 8 0 8 8 0 72 79 0 % P
% Gln: 8 0 0 0 8 0 0 8 8 0 0 8 0 0 0 % Q
% Arg: 0 0 8 0 0 0 65 0 0 0 8 0 0 8 0 % R
% Ser: 8 8 8 65 65 0 0 65 0 8 0 0 0 0 0 % S
% Thr: 8 0 8 8 0 0 0 0 0 0 0 0 8 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _