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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS12
All Species:
20.61
Human Site:
S254
Identified Species:
41.21
UniProt:
A0PJE2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0PJE2
NP_001026889.1
317
35146
S254
R
F
G
D
R
L
R
S
E
A
Q
G
A
D
T
Chimpanzee
Pan troglodytes
XP_001159419
317
35374
S254
R
F
R
D
R
L
R
S
E
A
Q
G
A
D
T
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYK4
316
35274
S252
C
L
L
W
R
L
F
S
P
F
F
K
S
T
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F389
414
46711
S351
L
A
R
P
F
T
K
S
M
Q
Q
G
A
A
T
Frog
Xenopus laevis
Q5XG41
318
34975
W252
A
K
I
R
K
P
T
W
D
K
P
S
P
E
T
Zebra Danio
Brachydanio rerio
Q803A8
412
46303
S348
L
A
R
P
F
T
K
S
M
Q
Q
G
A
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610310
330
36563
T267
M
I
W
P
L
L
K
T
P
K
S
G
A
Q
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17703
314
34587
F247
A
G
N
P
N
T
S
F
F
T
P
D
S
D
T
Sea Urchin
Strong. purpuratus
XP_001187701
321
35618
S256
R
F
K
D
K
L
R
S
P
E
Q
G
A
D
T
Poplar Tree
Populus trichocarpa
XP_002307520
322
35360
T260
S
L
S
G
K
L
R
T
S
E
E
G
A
D
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192713
322
35141
T260
S
F
A
G
K
L
R
T
S
E
Q
G
A
D
T
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
L207
L
V
E
T
E
F
S
L
V
R
Y
R
G
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
N.A.
N.A.
N.A.
33.4
N.A.
N.A.
N.A.
22.4
22.6
23.5
N.A.
36.6
N.A.
20.5
57.6
Protein Similarity:
100
97.4
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
N.A.
37.6
41.8
36.8
N.A.
50.9
N.A.
38.7
73.2
P-Site Identity:
100
93.3
N.A.
N.A.
N.A.
20
N.A.
N.A.
N.A.
33.3
6.6
33.3
N.A.
26.6
N.A.
13.3
73.3
P-Site Similarity:
100
93.3
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
40
26.6
40
N.A.
40
N.A.
20
80
Percent
Protein Identity:
40.9
N.A.
N.A.
43.1
20.1
N.A.
Protein Similarity:
56.8
N.A.
N.A.
59.6
38.4
N.A.
P-Site Identity:
40
N.A.
N.A.
53.3
0
N.A.
P-Site Similarity:
60
N.A.
N.A.
66.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
17
9
0
0
0
0
0
0
17
0
0
67
17
0
% A
% Cys:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
25
0
0
0
0
9
0
0
9
0
50
0
% D
% Glu:
0
0
9
0
9
0
0
0
17
25
9
0
0
9
9
% E
% Phe:
0
34
0
0
17
9
9
9
9
9
9
0
0
0
0
% F
% Gly:
0
9
9
17
0
0
0
0
0
0
0
67
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
0
34
0
25
0
0
17
0
9
0
0
0
% K
% Leu:
25
17
9
0
9
59
0
9
0
0
0
0
0
0
0
% L
% Met:
9
0
0
0
0
0
0
0
17
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
9
0
0
0
0
0
0
0
0
9
0
% N
% Pro:
0
0
0
34
0
9
0
0
25
0
17
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
17
50
0
0
9
0
% Q
% Arg:
25
0
25
9
25
0
42
0
0
9
0
9
0
0
0
% R
% Ser:
17
0
9
0
0
0
17
50
17
0
9
9
17
0
9
% S
% Thr:
0
0
0
9
0
25
9
25
0
9
0
0
0
9
84
% T
% Val:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
9
9
0
0
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _