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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHRS12
All Species:
7.58
Human Site:
S298
Identified Species:
15.15
UniProt:
A0PJE2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0PJE2
NP_001026889.1
317
35146
S298
P
L
A
T
A
S
S
S
P
A
E
E
E
K
L
Chimpanzee
Pan troglodytes
XP_001159419
317
35374
S298
P
L
A
R
T
S
S
S
P
A
E
E
E
K
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BYK4
316
35274
N296
W
V
S
S
R
A
R
N
K
K
T
A
E
R
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5F389
414
46711
V395
A
R
N
E
L
T
A
V
A
L
W
E
L
S
E
Frog
Xenopus laevis
Q5XG41
318
34975
A296
S
L
V
P
V
S
V
A
I
S
M
G
M
K
M
Zebra Danio
Brachydanio rerio
Q803A8
412
46303
L392
A
Q
D
P
A
A
A
L
S
L
W
E
L
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610310
330
36563
K311
A
L
D
D
K
V
A
K
F
L
W
A
E
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q17703
314
34587
D291
L
L
P
D
F
V
I
D
R
S
I
K
Q
T
S
Sea Urchin
Strong. purpuratus
XP_001187701
321
35618
S300
P
L
A
W
T
K
S
S
A
G
D
E
E
K
L
Poplar Tree
Populus trichocarpa
XP_002307520
322
35360
H304
F
S
A
T
R
G
S
H
S
L
I
N
N
I
V
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_192713
322
35141
H304
L
A
G
T
S
K
S
H
D
L
I
D
S
V
I
Baker's Yeast
Sacchar. cerevisiae
Q05016
267
29140
T251
Q
N
T
V
I
A
D
T
L
I
F
P
T
N
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
N.A.
N.A.
N.A.
33.4
N.A.
N.A.
N.A.
22.4
22.6
23.5
N.A.
36.6
N.A.
20.5
57.6
Protein Similarity:
100
97.4
N.A.
N.A.
N.A.
50.7
N.A.
N.A.
N.A.
37.6
41.8
36.8
N.A.
50.9
N.A.
38.7
73.2
P-Site Identity:
100
86.6
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
6.6
20
13.3
N.A.
13.3
N.A.
6.6
60
P-Site Similarity:
100
86.6
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
20
40
26.6
N.A.
20
N.A.
26.6
66.6
Percent
Protein Identity:
40.9
N.A.
N.A.
43.1
20.1
N.A.
Protein Similarity:
56.8
N.A.
N.A.
59.6
38.4
N.A.
P-Site Identity:
20
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
33.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
25
9
34
0
17
25
25
9
17
17
0
17
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
17
0
0
9
9
9
0
9
9
0
0
0
% D
% Glu:
0
0
0
9
0
0
0
0
0
0
17
42
42
0
25
% E
% Phe:
9
0
0
0
9
0
0
0
9
0
9
0
0
0
0
% F
% Gly:
0
0
9
0
0
9
0
0
0
9
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
9
0
9
0
9
9
25
0
0
9
9
% I
% Lys:
0
0
0
0
9
17
0
9
9
9
0
9
0
34
0
% K
% Leu:
17
50
0
0
9
0
0
9
9
42
0
0
17
0
34
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
9
% M
% Asn:
0
9
9
0
0
0
0
9
0
0
0
9
9
9
0
% N
% Pro:
25
0
9
17
0
0
0
0
17
0
0
9
0
0
0
% P
% Gln:
9
9
0
0
0
0
0
0
0
0
0
0
9
0
9
% Q
% Arg:
0
9
0
9
17
0
9
0
9
0
0
0
0
9
0
% R
% Ser:
9
9
9
9
9
25
42
25
17
17
0
0
9
25
9
% S
% Thr:
0
0
9
25
17
9
0
9
0
0
9
0
9
9
0
% T
% Val:
0
9
9
9
9
17
9
9
0
0
0
0
0
9
9
% V
% Trp:
9
0
0
9
0
0
0
0
0
0
25
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _