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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO1L2P
All Species:
7.27
Human Site:
S141
Identified Species:
16
UniProt:
A0PJM3
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0PJM3
XP_002342900
583
64243
S141
K
R
T
R
V
A
S
S
S
Q
R
S
R
G
S
Chimpanzee
Pan troglodytes
P48778
690
75343
A139
D
A
K
R
T
R
V
A
S
S
S
Q
R
S
S
Rhesus Macaque
Macaca mulatta
XP_001096198
1215
131336
G750
K
R
T
L
T
A
S
G
S
Q
P
S
N
G
P
Dog
Lupus familis
XP_533958
1655
172531
S1190
K
R
T
L
A
A
S
S
S
Q
P
P
N
G
P
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT28
1213
130772
S748
K
R
A
L
S
A
S
S
S
Q
A
S
H
G
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516921
311
35095
Chicken
Gallus gallus
XP_425887
1229
134673
S762
K
K
T
A
A
G
K
S
V
T
P
A
N
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001119888
1207
134661
R737
K
P
A
D
A
S
S
R
V
L
S
P
T
R
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733234
937
105604
K273
K
K
S
S
S
S
D
K
H
R
D
D
K
S
S
Honey Bee
Apis mellifera
XP_392195
1145
130995
D330
E
Q
I
D
S
Y
R
D
T
E
K
S
D
Y
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790674
215
24370
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.8
33.4
25.2
N.A.
32.3
N.A.
N.A.
31.2
29.5
N.A.
27.5
N.A.
25.5
21.6
N.A.
23.1
Protein Similarity:
100
82.4
40.1
29.4
N.A.
39.9
N.A.
N.A.
39.9
38.8
N.A.
36.7
N.A.
37.7
33.5
N.A.
31
P-Site Identity:
100
26.6
60
60
N.A.
60
N.A.
N.A.
0
26.6
N.A.
13.3
N.A.
13.3
6.6
N.A.
0
P-Site Similarity:
100
33.3
60
60
N.A.
60
N.A.
N.A.
0
40
N.A.
20
N.A.
46.6
40
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
10
28
37
0
10
0
0
10
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
19
0
0
10
10
0
0
10
10
10
10
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
10
0
10
0
0
0
0
0
37
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
64
19
10
0
0
0
10
10
0
0
10
0
10
0
0
% K
% Leu:
0
0
0
28
0
0
0
0
0
10
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
28
0
0
% N
% Pro:
0
10
0
0
0
0
0
0
0
0
28
19
0
0
28
% P
% Gln:
0
10
0
0
0
0
0
0
0
37
0
10
0
0
0
% Q
% Arg:
0
37
0
19
0
10
10
10
0
10
10
0
19
10
0
% R
% Ser:
0
0
10
10
28
19
46
37
46
10
19
37
0
19
37
% S
% Thr:
0
0
37
0
19
0
0
0
10
10
0
0
10
0
0
% T
% Val:
0
0
0
0
10
0
10
0
19
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _