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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
REXO1L2P
All Species:
4.55
Human Site:
Y452
Identified Species:
10
UniProt:
A0PJM3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.5
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0PJM3
XP_002342900
583
64243
Y452
P
D
N
E
I
V
D
Y
N
T
R
F
S
G
V
Chimpanzee
Pan troglodytes
P48778
690
75343
Y450
P
D
N
E
I
V
D
Y
N
T
R
F
S
G
V
Rhesus Macaque
Macaca mulatta
XP_001096198
1215
131336
D1096
K
P
D
N
E
I
V
D
Y
N
T
R
F
S
G
Dog
Lupus familis
XP_533958
1655
172531
D1536
K
P
D
N
E
I
V
D
Y
N
T
R
F
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q7TT28
1213
130772
D1094
K
P
D
N
E
V
V
D
Y
N
T
R
F
S
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516921
311
35095
V192
Y
N
T
R
F
S
G
V
T
E
E
N
L
K
N
Chicken
Gallus gallus
XP_425887
1229
134673
D1110
K
P
D
T
K
V
V
D
Y
N
T
R
F
S
G
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001119888
1207
134661
D1088
K
P
G
S
R
V
V
D
Y
N
T
R
F
S
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_733234
937
105604
I793
M
C
Y
T
T
H
G
I
E
L
T
R
V
T
V
Honey Bee
Apis mellifera
XP_392195
1145
130995
I980
T
L
P
K
N
T
P
I
E
E
Q
G
V
Y
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790674
215
24370
N96
D
N
E
V
V
D
H
N
T
R
F
S
G
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
81.8
33.4
25.2
N.A.
32.3
N.A.
N.A.
31.2
29.5
N.A.
27.5
N.A.
25.5
21.6
N.A.
23.1
Protein Similarity:
100
82.4
40.1
29.4
N.A.
39.9
N.A.
N.A.
39.9
38.8
N.A.
36.7
N.A.
37.7
33.5
N.A.
31
P-Site Identity:
100
100
0
0
N.A.
6.6
N.A.
N.A.
0
6.6
N.A.
6.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
13.3
13.3
N.A.
13.3
N.A.
N.A.
6.6
13.3
N.A.
6.6
N.A.
6.6
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
19
37
0
0
10
19
46
0
0
0
0
0
0
0
% D
% Glu:
0
0
10
19
28
0
0
0
19
19
10
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
10
19
46
0
0
% F
% Gly:
0
0
10
0
0
0
19
0
0
0
0
10
10
19
46
% G
% His:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
19
19
0
19
0
0
0
0
0
10
0
% I
% Lys:
46
0
0
10
10
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
0
0
0
0
0
0
0
10
0
0
10
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
19
28
10
0
0
10
19
46
0
10
0
0
10
% N
% Pro:
19
46
10
0
0
0
10
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
10
10
0
0
0
0
10
19
55
0
0
0
% R
% Ser:
0
0
0
10
0
10
0
0
0
0
0
10
19
46
0
% S
% Thr:
10
0
10
19
10
10
0
0
19
19
55
0
0
10
10
% T
% Val:
0
0
0
10
10
46
46
10
0
0
0
0
19
0
28
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
10
0
0
0
0
19
46
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _