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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FEZF1 All Species: 4.55
Human Site: S246 Identified Species: 10
UniProt: A0PJY2 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A0PJY2 NP_001019784.2 475 52038 S246 E K I A F K T S D F S R G S P
Chimpanzee Pan troglodytes A2T759 682 76399 N335 K A F R R S S N L I Q H Q R I
Rhesus Macaque Macaca mulatta XP_001093810 457 48679 K233 H P A P Y P H K E R L P A P L
Dog Lupus familis XP_848423 459 48733 K235 H P A P Y A H K E R L P A P L
Cat Felis silvestris
Mouse Mus musculus Q0VDQ9 475 51988 S246 E K I A F K T S D F S R G S P
Rat Rattus norvegicus Q4KLI1 562 63347 K325 E E K T G K E K K A P G P P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_414411 441 47591 R233 K E A A A A E R G G P P K G H
Frog Xenopus laevis Q9IAJ2 466 51991 A247 K I T F K T S A K F S S A S P
Zebra Danio Brachydanio rerio Q25C93 429 47376 L223 M K E S A H I L S E K L F K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608631 611 66423 D304 S P Q G S I E D S S P G S A S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_502594 218 25023 D12 S I E V L L A D S P S P K S L
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 23.8 54.7 54.7 N.A. 94.3 25.2 N.A. N.A. 53.4 73 62.1 N.A. 40.2 N.A. 34.7 N.A.
Protein Similarity: 100 36.2 64.6 64.4 N.A. 95.5 37.9 N.A. N.A. 60.6 81.2 72.8 N.A. 48.7 N.A. 39.1 N.A.
P-Site Identity: 100 0 0 0 N.A. 100 13.3 N.A. N.A. 6.6 26.6 6.6 N.A. 0 N.A. 13.3 N.A.
P-Site Similarity: 100 20 13.3 13.3 N.A. 100 20 N.A. N.A. 20 46.6 13.3 N.A. 6.6 N.A. 13.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 28 28 19 19 10 10 0 10 0 0 28 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 19 19 0 0 0 0 0 0 % D
% Glu: 28 19 19 0 0 0 28 0 19 10 0 0 0 0 0 % E
% Phe: 0 0 10 10 19 0 0 0 0 28 0 0 10 0 0 % F
% Gly: 0 0 0 10 10 0 0 0 10 10 0 19 19 10 0 % G
% His: 19 0 0 0 0 10 19 0 0 0 0 10 0 0 10 % H
% Ile: 0 19 19 0 0 10 10 0 0 10 0 0 0 0 10 % I
% Lys: 28 28 10 0 10 28 0 28 19 0 10 0 19 10 0 % K
% Leu: 0 0 0 0 10 10 0 10 10 0 19 10 0 0 28 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % N
% Pro: 0 28 0 19 0 10 0 0 0 10 28 37 10 28 28 % P
% Gln: 0 0 10 0 0 0 0 0 0 0 10 0 10 0 0 % Q
% Arg: 0 0 0 10 10 0 0 10 0 19 0 19 0 10 0 % R
% Ser: 19 0 0 10 10 10 19 19 28 10 37 10 10 37 10 % S
% Thr: 0 0 10 10 0 10 19 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _