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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP10
All Species:
14.24
Human Site:
T586
Identified Species:
34.81
UniProt:
A1A4S6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A1A4S6
NP_078881.3
786
89375
T586
D
T
T
F
P
E
P
T
C
L
S
A
S
P
P
Chimpanzee
Pan troglodytes
Q7YQL6
802
91596
P568
G
K
I
Y
L
G
P
P
E
E
S
A
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001096942
795
89860
T595
D
T
T
F
P
E
P
T
C
L
S
A
S
P
P
Dog
Lupus familis
XP_539757
786
89529
I586
D
A
T
F
P
E
P
I
P
L
S
T
S
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6Y5D8
786
89347
T586
D
T
T
F
A
E
P
T
C
L
S
A
S
P
P
Rat
Rattus norvegicus
P0CAX5
802
91820
S571
Y
L
G
P
P
E
D
S
Q
V
P
P
V
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510811
874
99203
T670
D
A
T
L
S
E
P
T
S
M
S
I
S
P
P
Chicken
Gallus gallus
Q5ZMW5
760
86506
H564
I
E
I
L
I
E
N
H
E
K
I
F
N
T
V
Frog
Xenopus laevis
Q5U4T3
771
87657
T570
N
Y
E
E
M
F
S
T
V
P
E
M
P
Q
T
Zebra Danio
Brachydanio rerio
Q6ZM89
805
91116
H584
D
P
N
V
P
L
P
H
P
Q
S
H
S
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
91.5
93.7
N.A.
91.4
43.6
N.A.
74.4
57.6
54.9
48.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
61.9
94
95.5
N.A.
94.2
61.3
N.A.
79.4
73.2
71.3
63.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
100
73.3
N.A.
93.3
26.6
N.A.
60
6.6
6.6
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
100
73.3
N.A.
93.3
40
N.A.
66.6
13.3
13.3
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
10
0
0
0
0
0
0
40
10
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
30
0
0
0
0
0
0
% C
% Asp:
60
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
10
10
10
0
70
0
0
20
10
10
0
0
0
0
% E
% Phe:
0
0
0
40
0
10
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
0
10
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
20
0
0
0
10
0
0
0
% H
% Ile:
10
0
20
0
10
0
0
10
0
0
10
10
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
0
10
0
20
10
10
0
0
0
40
0
0
0
0
0
% L
% Met:
0
0
0
0
10
0
0
0
0
10
0
10
0
0
0
% M
% Asn:
10
0
10
0
0
0
10
0
0
0
0
0
10
0
0
% N
% Pro:
0
10
0
10
50
0
70
10
20
10
10
10
10
70
70
% P
% Gln:
0
0
0
0
0
0
0
0
10
10
0
0
0
20
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
10
0
10
10
10
0
70
0
60
0
10
% S
% Thr:
0
30
50
0
0
0
0
50
0
0
0
10
0
10
10
% T
% Val:
0
0
0
10
0
0
0
0
10
10
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _