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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXDNL All Species: 4.55
Human Site: S68 Identified Species: 10
UniProt: A1KZ92 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A1KZ92 NP_653252.3 1463 163654 S68 R I R E I P G S A F K K L K N
Chimpanzee Pan troglodytes XP_519754 1463 163608 S68 R I R E I P G S A F K K L K N
Rhesus Macaque Macaca mulatta XP_001108296 1316 146985
Dog Lupus familis XP_544073 1296 144318
Cat Felis silvestris
Mouse Mus musculus Q3UQ28 1475 165115 G77 R I R E I Q P G A F R R L R S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514779 1469 164647 N68 R I Q E I P A N S F K K L K N
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665312 1530 170912 G75 K I K D L Q P G S F K R L K N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 N70 H I E E L P A N A F S G L A Q
Honey Bee Apis mellifera XP_396476 1293 147180
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318
Sea Urchin Strong. purpuratus XP_001186212 1421 158781 R80 R I A D I E E R A F E G L N N
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 85.2 71.8 N.A. 60 N.A. N.A. 71.6 N.A. N.A. 54.1 N.A. 37.7 38.4 32.4 42
Protein Similarity: 100 99.3 87.2 78.1 N.A. 73.6 N.A. N.A. 82 N.A. N.A. 68.8 N.A. 54 54.6 49.2 57
P-Site Identity: 100 100 0 0 N.A. 53.3 N.A. N.A. 73.3 N.A. N.A. 40 N.A. 40 0 0 46.6
P-Site Similarity: 100 100 0 0 N.A. 80 N.A. N.A. 93.3 N.A. N.A. 80 N.A. 53.3 0 0 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 19 0 46 0 0 0 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 10 46 0 10 10 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 64 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 19 19 0 0 0 19 0 0 0 % G
% His: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 64 0 0 46 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 10 0 10 0 0 0 0 0 0 0 37 28 0 37 0 % K
% Leu: 0 0 0 0 19 0 0 0 0 0 0 0 64 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 19 0 0 0 0 0 10 46 % N
% Pro: 0 0 0 0 0 37 19 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 19 0 0 0 0 0 0 0 0 10 % Q
% Arg: 46 0 28 0 0 0 0 10 0 0 10 19 0 10 0 % R
% Ser: 0 0 0 0 0 0 0 19 19 0 10 0 0 0 10 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _