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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PXDNL All Species: 16.36
Human Site: Y1281 Identified Species: 36
UniProt: A1KZ92 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A1KZ92 NP_653252.3 1463 163654 Y1281 K A E Y P Q D Y L N C S E I P
Chimpanzee Pan troglodytes XP_519754 1463 163608 Y1281 K A E Y P Q D Y L S C S E I P
Rhesus Macaque Macaca mulatta XP_001108296 1316 146985 D1147 T I I Q R G R D H G I P P Y V
Dog Lupus familis XP_544073 1296 144318 M1127 I P Q V D L R M W Q D C C E D
Cat Felis silvestris
Mouse Mus musculus Q3UQ28 1475 165115 Y1295 V A E F P H G Y S S C E D I P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514779 1469 164647 Y1285 K A E Y P H G Y V S C D E I P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665312 1530 170912 Y1355 V A D L P H G Y G S C A D L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VZZ4 1527 170496 Y1333 L A K H Q G G Y K K C E D I I
Honey Bee Apis mellifera XP_396476 1293 147180 L1124 P N A K V G P L F K C L L L E
Nematode Worm Caenorhab. elegans Q1ENI8 1285 146318 G1115 Q N I D L W V G G I V E E K L
Sea Urchin Strong. purpuratus XP_001186212 1421 158781 E1252 E G D R F W Y E N P G V F S P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 85.2 71.8 N.A. 60 N.A. N.A. 71.6 N.A. N.A. 54.1 N.A. 37.7 38.4 32.4 42
Protein Similarity: 100 99.3 87.2 78.1 N.A. 73.6 N.A. N.A. 82 N.A. N.A. 68.8 N.A. 54 54.6 49.2 57
P-Site Identity: 100 93.3 0 0 N.A. 46.6 N.A. N.A. 66.6 N.A. N.A. 33.3 N.A. 26.6 6.6 6.6 6.6
P-Site Similarity: 100 100 0 6.6 N.A. 66.6 N.A. N.A. 80 N.A. N.A. 66.6 N.A. 46.6 13.3 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 55 10 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 64 10 10 0 0 % C
% Asp: 0 0 19 10 10 0 19 10 0 0 10 10 28 0 10 % D
% Glu: 10 0 37 0 0 0 0 10 0 0 0 28 37 10 10 % E
% Phe: 0 0 0 10 10 0 0 0 10 0 0 0 10 0 0 % F
% Gly: 0 10 0 0 0 28 37 10 19 10 10 0 0 0 0 % G
% His: 0 0 0 10 0 28 0 0 10 0 0 0 0 0 0 % H
% Ile: 10 10 19 0 0 0 0 0 0 10 10 0 0 46 10 % I
% Lys: 28 0 10 10 0 0 0 0 10 19 0 0 0 10 0 % K
% Leu: 10 0 0 10 10 10 0 10 19 0 0 10 10 19 10 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % M
% Asn: 0 19 0 0 0 0 0 0 10 10 0 0 0 0 0 % N
% Pro: 10 10 0 0 46 0 10 0 0 10 0 10 10 0 55 % P
% Gln: 10 0 10 10 10 19 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 10 10 0 19 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 0 10 37 0 19 0 10 0 % S
% Thr: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 19 0 0 10 10 0 10 0 10 0 10 10 0 0 10 % V
% Trp: 0 0 0 0 0 19 0 0 10 0 0 0 0 0 0 % W
% Tyr: 0 0 0 28 0 0 10 55 0 0 0 0 0 10 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _