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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 22.73
Human Site: S131 Identified Species: 38.46
UniProt: A1L167 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A1L167 NP_001138633.1 161 18338 S131 K A G K S K K S F S R K E A E
Chimpanzee Pan troglodytes XP_001175391 291 30996 S261 K A G K S K K S F S R K E A E
Rhesus Macaque Macaca mulatta XP_001111833 440 48588 Q410 Q F G A N K S Q Y S L T R A Q
Dog Lupus familis XP_545181 161 18311 S131 K A G K S K K S F S R K E A E
Cat Felis silvestris
Mouse Mus musculus A0PJN4 161 18346 S131 K A G K S K K S F S R K E A E
Rat Rattus norvegicus NP_001138635 304 32633 S274 K A G K S K K S F S R K E A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511100 387 42275 S357 K A G K S K K S F S R K E A E
Chicken Gallus gallus XP_413740 404 45007 Q374 Q F G A N K N Q Y N L A R A Q
Frog Xenopus laevis NP_001083463 368 41875 Q338 Q F G A N K N Q Y N L A R A Q
Zebra Danio Brachydanio rerio XP_685644 279 31471 A249 K A G K S K K A F S R K E A E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM35 306 33651 F277 K P K S T K E F T R R Q A E E
Honey Bee Apis mellifera XP_395821 261 29512 F232 K P K T N K E F N R R S A E E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795879 448 48805 P418 S S F R S D V P F N K Q E A E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P52492 156 17735 L127 E P N N R S P L N A V A A E L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.9 22.2 98.7 N.A. 98.7 52.2 N.A. 41 23.7 25.5 53.7 N.A. 36.2 40.2 N.A. 21.8
Protein Similarity: 100 54.9 29.3 98.7 N.A. 100 52.9 N.A. 41.5 31.1 34.2 56.6 N.A. 45.4 54.4 N.A. 29
P-Site Identity: 100 100 26.6 100 N.A. 100 100 N.A. 100 20 20 93.3 N.A. 26.6 26.6 N.A. 33.3
P-Site Similarity: 100 100 53.3 100 N.A. 100 100 N.A. 100 53.3 53.3 100 N.A. 46.6 40 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 50 0 22 0 0 0 8 0 8 0 22 22 79 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 0 % D
% Glu: 8 0 0 0 0 0 15 0 0 0 0 0 58 22 72 % E
% Phe: 0 22 8 0 0 0 0 15 58 0 0 0 0 0 0 % F
% Gly: 0 0 72 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 65 0 15 50 0 86 50 0 0 0 8 50 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 8 0 0 22 0 0 0 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 8 29 0 15 0 15 22 0 0 0 0 0 % N
% Pro: 0 22 0 0 0 0 8 8 0 0 0 0 0 0 0 % P
% Gln: 22 0 0 0 0 0 0 22 0 0 0 15 0 0 22 % Q
% Arg: 0 0 0 8 8 0 0 0 0 15 65 0 22 0 0 % R
% Ser: 8 8 0 8 58 8 8 43 0 58 0 8 0 0 0 % S
% Thr: 0 0 0 8 8 0 0 0 8 0 0 8 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 0 8 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 22 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _