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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 38.18
Human Site: S143 Identified Species: 64.62
UniProt: A1L167 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A1L167 NP_001138633.1 161 18338 S143 E A E A T F K S L V K T H E K
Chimpanzee Pan troglodytes XP_001175391 291 30996 S273 E A E A T F K S L V K T H E K
Rhesus Macaque Macaca mulatta XP_001111833 440 48588 S422 R A Q Q S Y K S L V Q I H E K
Dog Lupus familis XP_545181 161 18311 S143 E A E A T F K S L V K T H E K
Cat Felis silvestris
Mouse Mus musculus A0PJN4 161 18346 S143 E A E A T F K S L V K T H E K
Rat Rattus norvegicus NP_001138635 304 32633 S286 E A E A T F K S L V K T H E K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511100 387 42275 S369 E A E A T F K S L V K T H E K
Chicken Gallus gallus XP_413740 404 45007 S386 R A Q Q S Y K S L V Q I H E K
Frog Xenopus laevis NP_001083463 368 41875 S350 R A Q Q S Y K S L V Q I H E K
Zebra Danio Brachydanio rerio XP_685644 279 31471 S261 E A E A T F K S L V K T H E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM35 306 33651 L289 A E E S F R S L V K T H E K Y
Honey Bee Apis mellifera XP_395821 261 29512 L244 A E E S F R S L V K T H E K Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795879 448 48805 A430 E A E V S F R A I V E T H E R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P52492 156 17735 M139 A E L W D A D M E E Y R K K V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.9 22.2 98.7 N.A. 98.7 52.2 N.A. 41 23.7 25.5 53.7 N.A. 36.2 40.2 N.A. 21.8
Protein Similarity: 100 54.9 29.3 98.7 N.A. 100 52.9 N.A. 41.5 31.1 34.2 56.6 N.A. 45.4 54.4 N.A. 29
P-Site Identity: 100 100 53.3 100 N.A. 100 100 N.A. 100 53.3 53.3 100 N.A. 6.6 6.6 N.A. 53.3
P-Site Similarity: 100 100 80 100 N.A. 100 100 N.A. 100 80 80 100 N.A. 26.6 26.6 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 22 79 0 50 0 8 0 8 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 8 0 8 0 0 0 0 0 0 0 0 % D
% Glu: 58 22 72 0 0 0 0 0 8 8 8 0 15 79 0 % E
% Phe: 0 0 0 0 15 58 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 15 79 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 8 0 0 22 0 0 0 % I
% Lys: 0 0 0 0 0 0 72 0 0 15 50 0 8 22 72 % K
% Leu: 0 0 8 0 0 0 0 15 72 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 22 22 0 0 0 0 0 0 22 0 0 0 0 % Q
% Arg: 22 0 0 0 0 15 8 0 0 0 0 8 0 0 8 % R
% Ser: 0 0 0 15 29 0 15 72 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 50 0 0 0 0 0 15 58 0 0 0 % T
% Val: 0 0 0 8 0 0 0 0 15 79 0 0 0 0 8 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 22 0 0 0 0 8 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _