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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: All Species: 31.52
Human Site: T147 Identified Species: 53.33
UniProt: A1L167 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A1L167 NP_001138633.1 161 18338 T147 T F K S L V K T H E K Y G W V
Chimpanzee Pan troglodytes XP_001175391 291 30996 T277 T F K S L V K T H E K Y G W V
Rhesus Macaque Macaca mulatta XP_001111833 440 48588 I426 S Y K S L V Q I H E K N G W Y
Dog Lupus familis XP_545181 161 18311 T147 T F K S L V K T H E K Y G W V
Cat Felis silvestris
Mouse Mus musculus A0PJN4 161 18346 T147 T F K S L V K T H E K Y G W V
Rat Rattus norvegicus NP_001138635 304 32633 T290 T F K S L V K T H E K Y G W V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511100 387 42275 T373 T F K S L V K T H E K Y G W V
Chicken Gallus gallus XP_413740 404 45007 I390 S Y K S L V Q I H E K N G W Y
Frog Xenopus laevis NP_001083463 368 41875 I354 S Y K S L V Q I H E K N G W Y
Zebra Danio Brachydanio rerio XP_685644 279 31471 T265 T F K S L V K T H E K Y G W V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VM35 306 33651 H293 F R S L V K T H E K Y G W V T
Honey Bee Apis mellifera XP_395821 261 29512 H248 F R S L V K T H E K Y G W V T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795879 448 48805 T434 S F R A I V E T H E R Y G W H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P52492 156 17735 R143 D A D M E E Y R K K V L A C Y
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 54.9 22.2 98.7 N.A. 98.7 52.2 N.A. 41 23.7 25.5 53.7 N.A. 36.2 40.2 N.A. 21.8
Protein Similarity: 100 54.9 29.3 98.7 N.A. 100 52.9 N.A. 41.5 31.1 34.2 56.6 N.A. 45.4 54.4 N.A. 29
P-Site Identity: 100 100 60 100 N.A. 100 100 N.A. 100 60 60 100 N.A. 0 0 N.A. 53.3
P-Site Similarity: 100 100 80 100 N.A. 100 100 N.A. 100 80 80 100 N.A. 13.3 13.3 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.9 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 41.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 0 0 0 0 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 8 8 8 0 15 79 0 0 0 0 0 % E
% Phe: 15 58 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 15 79 0 0 % G
% His: 0 0 0 0 0 0 0 15 79 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 8 0 0 22 0 0 0 0 0 0 0 % I
% Lys: 0 0 72 0 0 15 50 0 8 22 72 0 0 0 0 % K
% Leu: 0 0 0 15 72 0 0 0 0 0 0 8 0 0 0 % L
% Met: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 22 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 22 0 0 0 0 0 0 0 0 % Q
% Arg: 0 15 8 0 0 0 0 8 0 0 8 0 0 0 0 % R
% Ser: 29 0 15 72 0 0 0 0 0 0 0 0 0 0 0 % S
% Thr: 50 0 0 0 0 0 15 58 0 0 0 0 0 0 15 % T
% Val: 0 0 0 0 15 79 0 0 0 0 8 0 0 15 50 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 15 79 0 % W
% Tyr: 0 22 0 0 0 0 8 0 0 0 15 58 0 0 29 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _