KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG3
All Species:
10.91
Human Site:
T863
Identified Species:
40
UniProt:
A1L390
Number Species:
6
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A1L390
NP_056364.1
1219
134412
T863
A
I
T
E
E
S
A
T
A
S
P
E
S
S
S
Chimpanzee
Pan troglodytes
XP_510005
1446
158066
T1090
A
I
T
E
E
S
A
T
A
S
P
E
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001098617
1385
155017
S905
A
L
L
T
P
V
K
S
R
A
G
R
A
S
H
Dog
Lupus familis
XP_854222
1192
131043
T840
A
I
T
E
E
S
A
T
A
S
P
E
S
A
S
Cat
Felis silvestris
Mouse
Mus musculus
Q4VAC9
1341
148554
V983
A
I
T
E
E
S
A
V
A
S
P
E
S
A
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506571
1331
147843
E987
H
E
L
G
A
I
A
E
E
L
P
G
A
S
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396694
1354
153015
D1014
R
P
F
T
I
A
S
D
K
P
A
E
I
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74.6
28.3
73.8
N.A.
73.7
N.A.
N.A.
56.9
N.A.
N.A.
N.A.
N.A.
N.A.
22.9
N.A.
N.A.
Protein Similarity:
100
77.2
44.1
79.7
N.A.
79.1
N.A.
N.A.
65.4
N.A.
N.A.
N.A.
N.A.
N.A.
40.4
N.A.
N.A.
P-Site Identity:
100
100
13.3
93.3
N.A.
86.6
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
100
100
40
100
N.A.
93.3
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
72
0
0
0
15
15
72
0
58
15
15
0
29
29
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% D
% Glu:
0
15
0
58
58
0
0
15
15
0
0
72
0
0
0
% E
% Phe:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
15
0
0
0
0
0
0
15
15
0
0
0
% G
% His:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% H
% Ile:
0
58
0
0
15
15
0
0
0
0
0
0
15
0
0
% I
% Lys:
0
0
0
0
0
0
15
0
15
0
0
0
0
0
0
% K
% Leu:
0
15
29
0
0
0
0
0
0
15
0
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
0
% N
% Pro:
0
15
0
0
15
0
0
0
0
15
72
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
15
0
0
0
0
0
0
0
15
0
0
15
0
0
0
% R
% Ser:
0
0
0
0
0
58
15
15
0
58
0
0
58
58
72
% S
% Thr:
0
0
58
29
0
0
0
43
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
15
0
15
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _