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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MPN2 All Species: 16.36
Human Site: S192 Identified Species: 51.43
UniProt: A1L453 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A1L453 NP_898885.1 326 35356 S192 A T G W G L V S K Q G E T S D
Chimpanzee Pan troglodytes XP_525080 326 35266 S192 A T G W G L V S K Q G E T S D
Rhesus Macaque Macaca mulatta XP_001086001 326 35234 S192 A T G W G L V S K Q G E T S D
Dog Lupus familis XP_532412 334 36753 S200 A T G W G L I S P Q G Y V T D
Cat Felis silvestris
Mouse Mus musculus Q3UKY7 322 35679 S188 T T G W G M I S P Q G E T G N
Rat Rattus norvegicus Q6BEA2 328 35785 Q182 L P N P R I L Q K L A V P L I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516983 294 32833 W167 T K C W V T G W G N I K E N E
Chicken Gallus gallus
Frog Xenopus laevis NP_001090463 358 38806 K179 S S P K T L Q K A E V G I I D
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 92 64 N.A. 57.3 40.5 N.A. 35.2 N.A. 32.4 N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99 95.4 78.1 N.A. 73.9 55.1 N.A. 52.1 N.A. 50.8 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 66.6 N.A. 60 6.6 N.A. 6.6 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 80 N.A. 80 20 N.A. 26.6 N.A. 33.3 N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 0 0 0 0 0 0 0 13 0 13 0 0 0 0 % A
% Cys: 0 0 13 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 63 % D
% Glu: 0 0 0 0 0 0 0 0 0 13 0 50 13 0 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 63 0 63 0 13 0 13 0 63 13 0 13 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 13 25 0 0 0 13 0 13 13 13 % I
% Lys: 0 13 0 13 0 0 0 13 50 0 0 13 0 0 0 % K
% Leu: 13 0 0 0 0 63 13 0 0 13 0 0 0 13 0 % L
% Met: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 13 0 0 0 0 0 0 13 0 0 0 13 13 % N
% Pro: 0 13 13 13 0 0 0 0 25 0 0 0 13 0 0 % P
% Gln: 0 0 0 0 0 0 13 13 0 63 0 0 0 0 0 % Q
% Arg: 0 0 0 0 13 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 13 0 0 0 0 0 63 0 0 0 0 0 38 0 % S
% Thr: 25 63 0 0 13 13 0 0 0 0 0 0 50 13 0 % T
% Val: 0 0 0 0 13 0 38 0 0 0 13 13 13 0 0 % V
% Trp: 0 0 0 75 0 0 0 13 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _