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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MPN2
All Species:
16.67
Human Site:
Y274
Identified Species:
52.38
UniProt:
A1L453
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A1L453
NP_898885.1
326
35356
Y274
R
G
C
S
N
P
L
Y
P
G
V
Y
A
S
V
Chimpanzee
Pan troglodytes
XP_525080
326
35266
Y274
R
G
C
S
N
P
L
Y
P
G
V
Y
A
S
V
Rhesus Macaque
Macaca mulatta
XP_001086001
326
35234
Y274
R
G
C
T
N
P
L
Y
P
G
V
Y
A
S
V
Dog
Lupus familis
XP_532412
334
36753
Y282
R
G
C
T
Y
P
M
Y
P
A
V
Y
T
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q3UKY7
322
35679
Y270
R
G
C
A
Q
P
L
Y
P
G
V
F
A
N
V
Rat
Rattus norvegicus
Q6BEA2
328
35785
R261
E
G
C
A
R
R
N
R
P
G
V
Y
I
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516983
294
32833
G243
N
N
A
W
T
L
I
G
V
V
S
W
G
H
G
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001090463
358
38806
R257
F
G
C
A
E
P
D
R
P
G
V
Y
T
K
V
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
92
64
N.A.
57.3
40.5
N.A.
35.2
N.A.
32.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
95.4
78.1
N.A.
73.9
55.1
N.A.
52.1
N.A.
50.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
60
N.A.
73.3
46.6
N.A.
0
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
73.3
N.A.
93.3
53.3
N.A.
13.3
N.A.
60
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
13
38
0
0
0
0
0
13
0
0
50
0
0
% A
% Cys:
0
0
88
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% D
% Glu:
13
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
13
0
0
0
% F
% Gly:
0
88
0
0
0
0
0
13
0
75
0
0
13
0
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
0
0
13
0
0
0
0
0
13
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% K
% Leu:
0
0
0
0
0
13
50
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% M
% Asn:
13
13
0
0
38
0
13
0
0
0
0
0
0
13
0
% N
% Pro:
0
0
0
0
0
75
0
0
88
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
63
0
0
0
13
13
0
25
0
0
0
0
0
25
0
% R
% Ser:
0
0
0
25
0
0
0
0
0
0
13
0
0
38
0
% S
% Thr:
0
0
0
25
13
0
0
0
0
0
0
0
25
0
0
% T
% Val:
0
0
0
0
0
0
0
0
13
13
88
0
0
0
88
% V
% Trp:
0
0
0
13
0
0
0
0
0
0
0
13
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
63
0
0
0
75
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _