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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3PXD2B
All Species:
18.18
Human Site:
S499
Identified Species:
44.44
UniProt:
A1X283
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A1X283
NP_001017995.1
911
101579
S499
K
D
V
L
R
K
A
S
S
D
M
S
A
S
A
Chimpanzee
Pan troglodytes
XP_527118
910
101653
S498
K
D
V
L
R
K
A
S
S
D
M
S
A
S
A
Rhesus Macaque
Macaca mulatta
XP_001095586
909
101173
S499
K
E
V
L
R
K
A
S
S
D
M
S
A
S
A
Dog
Lupus familis
XP_546237
884
98219
S480
K
E
V
P
R
K
A
S
S
D
M
S
S
C
A
Cat
Felis silvestris
Mouse
Mus musculus
A2AAY5
908
101499
S499
K
E
A
P
R
K
A
S
S
D
L
S
A
S
T
Rat
Rattus norvegicus
NP_001101076
1073
118192
R527
N
E
E
P
T
E
D
R
G
S
G
D
K
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507279
907
99999
A510
G
K
Q
P
P
W
N
A
S
A
A
T
S
G
L
Chicken
Gallus gallus
XP_425197
845
94032
A472
A
T
E
S
G
D
L
A
F
T
C
G
Y
E
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LYG0
1119
124887
K576
D
C
N
P
P
K
P
K
T
H
N
S
P
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783086
618
67562
T247
E
D
E
I
S
F
E
T
G
V
V
V
T
V
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
97.9
87.1
N.A.
87.5
35.7
N.A.
70.6
68.5
N.A.
35.6
N.A.
N.A.
N.A.
N.A.
30.5
Protein Similarity:
100
97.9
98.6
91.4
N.A.
91.7
49.1
N.A.
80.4
79
N.A.
49.7
N.A.
N.A.
N.A.
N.A.
43.9
P-Site Identity:
100
100
93.3
73.3
N.A.
66.6
0
N.A.
6.6
0
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
13.3
N.A.
26.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
50
20
0
10
10
0
40
0
40
% A
% Cys:
0
10
0
0
0
0
0
0
0
0
10
0
0
10
0
% C
% Asp:
10
30
0
0
0
10
10
0
0
50
0
10
0
0
0
% D
% Glu:
10
40
30
0
0
10
10
0
0
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
10
0
0
10
0
0
0
0
0
0
% F
% Gly:
10
0
0
0
10
0
0
0
20
0
10
10
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
50
10
0
0
0
60
0
10
0
0
0
0
10
10
0
% K
% Leu:
0
0
0
30
0
0
10
0
0
0
10
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
40
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
10
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
50
20
0
10
0
0
0
0
0
10
0
20
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
50
0
0
10
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
10
10
0
0
50
60
10
0
60
20
40
0
% S
% Thr:
0
10
0
0
10
0
0
10
10
10
0
10
10
0
10
% T
% Val:
0
0
40
0
0
0
0
0
0
10
10
10
0
10
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _