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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SH3PXD2B
All Species:
17.58
Human Site:
S521
Identified Species:
42.96
UniProt:
A1X283
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A1X283
NP_001017995.1
911
101579
S521
P
D
M
E
E
K
P
S
L
P
P
R
K
E
S
Chimpanzee
Pan troglodytes
XP_527118
910
101653
S520
P
D
M
E
E
K
P
S
L
P
P
R
K
E
S
Rhesus Macaque
Macaca mulatta
XP_001095586
909
101173
S521
P
D
M
E
E
K
P
S
L
P
P
R
K
E
S
Dog
Lupus familis
XP_546237
884
98219
S502
P
D
L
E
E
K
P
S
L
P
P
R
K
E
S
Cat
Felis silvestris
Mouse
Mus musculus
A2AAY5
908
101499
S521
P
T
Q
E
E
K
P
S
L
P
P
R
K
E
S
Rat
Rattus norvegicus
NP_001101076
1073
118192
A549
P
A
S
S
L
Q
R
A
H
F
K
V
G
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507279
907
99999
P532
D
P
D
A
E
E
K
P
S
L
P
P
R
K
E
Chicken
Gallus gallus
XP_425197
845
94032
R494
E
K
P
S
L
P
P
R
K
E
S
I
I
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1LYG0
1119
124887
E598
K
S
N
P
A
A
A
E
R
I
A
Q
A
G
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783086
618
67562
K269
W
K
V
S
Y
Q
G
K
Q
G
W
A
P
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
97.9
87.1
N.A.
87.5
35.7
N.A.
70.6
68.5
N.A.
35.6
N.A.
N.A.
N.A.
N.A.
30.5
Protein Similarity:
100
97.9
98.6
91.4
N.A.
91.7
49.1
N.A.
80.4
79
N.A.
49.7
N.A.
N.A.
N.A.
N.A.
43.9
P-Site Identity:
100
100
100
93.3
N.A.
86.6
20
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
86.6
33.3
N.A.
33.3
20
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
10
10
10
10
10
0
0
10
10
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
40
10
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
50
60
10
0
10
0
10
0
0
0
60
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
0
10
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% I
% Lys:
10
20
0
0
0
50
10
10
10
0
10
0
50
20
10
% K
% Leu:
0
0
10
0
20
0
0
0
50
10
0
0
0
0
0
% L
% Met:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
60
10
10
10
0
10
60
10
0
50
60
10
10
0
0
% P
% Gln:
0
0
10
0
0
20
0
0
10
0
0
10
0
0
0
% Q
% Arg:
0
0
0
0
0
0
10
10
10
0
0
50
10
0
0
% R
% Ser:
0
10
10
30
0
0
0
50
10
0
10
0
0
0
70
% S
% Thr:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _