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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3H12D
All Species:
1.21
Human Site:
T470
Identified Species:
4.44
UniProt:
A2A288
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A288
NP_997243.1
527
58078
T470
G
G
L
S
V
Y
A
T
E
D
D
E
G
D
A
Chimpanzee
Pan troglodytes
XP_518794
527
57829
A470
G
G
L
S
V
Y
A
A
E
D
D
E
G
N
A
Rhesus Macaque
Macaca mulatta
XP_001087043
526
57505
A470
G
G
L
S
G
Y
A
A
E
D
E
G
E
A
R
Dog
Lupus familis
XP_541146
627
68793
S568
G
L
L
L
Q
S
L
S
Y
H
W
V
H
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BIY3
533
59322
Q480
R
G
P
S
E
S
A
Q
P
V
A
N
G
G
G
Rat
Rattus norvegicus
A0JPN4
596
65909
P517
E
Y
W
S
E
P
Y
P
L
P
P
P
T
P
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511586
622
68204
R549
P
A
R
A
A
A
L
R
D
P
H
R
L
V
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98
94.1
45.4
N.A.
64.7
40.7
N.A.
39.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
95.2
51.9
N.A.
72
50
N.A.
49.8
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
86.6
53.3
20
N.A.
26.6
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
60
26.6
N.A.
26.6
6.6
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
15
0
15
15
15
58
29
0
0
15
0
0
15
58
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
15
43
29
0
0
15
0
% D
% Glu:
15
0
0
0
29
0
0
0
43
0
15
29
15
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
58
58
0
0
15
0
0
0
0
0
0
15
43
15
15
% G
% His:
0
0
0
0
0
0
0
0
0
15
15
0
15
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
15
58
15
0
0
29
0
15
0
0
0
15
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
15
0
15
0
% N
% Pro:
15
0
15
0
0
15
0
15
15
29
15
15
0
15
0
% P
% Gln:
0
0
0
0
15
0
0
15
0
0
0
0
0
0
0
% Q
% Arg:
15
0
15
0
0
0
0
15
0
0
0
15
0
0
15
% R
% Ser:
0
0
0
72
0
29
0
15
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
15
0
0
0
0
15
0
0
% T
% Val:
0
0
0
0
29
0
0
0
0
15
0
15
0
15
15
% V
% Trp:
0
0
15
0
0
0
0
0
0
0
15
0
0
0
0
% W
% Tyr:
0
15
0
0
0
43
15
0
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _