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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD3
All Species:
14.85
Human Site:
S365
Identified Species:
27.22
UniProt:
A2A2Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A2Y4
NP_777598.3
597
68772
S365
A
N
I
T
Q
S
R
S
S
H
S
L
N
K
Q
Chimpanzee
Pan troglodytes
XP_520094
581
66659
S349
A
N
I
T
Q
S
R
S
S
H
S
L
N
K
Q
Rhesus Macaque
Macaca mulatta
XP_001102733
838
94037
K629
E
V
V
E
A
S
S
K
I
Q
R
E
P
P
E
Dog
Lupus familis
XP_541268
582
66957
S351
A
N
I
T
Q
S
R
S
S
Y
S
L
N
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD4
595
68429
S365
V
N
I
T
Q
S
R
S
F
H
S
L
N
K
Q
Rat
Rattus norvegicus
Q5FVG2
731
81700
A399
G
S
V
H
N
A
S
A
Q
N
N
D
S
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510887
421
48616
R220
H
G
S
R
V
T
A
R
N
A
G
A
P
L
L
Chicken
Gallus gallus
XP_413944
395
45595
N194
T
P
A
T
S
E
L
N
F
L
R
K
A
Q
T
Frog
Xenopus laevis
P11434
801
89411
R524
T
G
S
K
R
A
S
R
S
L
D
G
A
A
V
Zebra Danio
Brachydanio rerio
O57457
619
70690
G361
K
R
S
T
Q
P
A
G
R
N
N
G
G
Q
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609384
572
64686
S350
S
S
K
R
K
A
S
S
V
P
A
T
P
S
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
F365
R
S
L
S
K
S
S
F
L
R
S
T
F
S
G
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
A348
E
G
F
S
T
H
L
A
N
Q
N
H
S
T
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
65.5
94.1
N.A.
91.2
29.1
N.A.
50.5
42.5
23.3
28.7
N.A.
30.1
N.A.
20.2
30.4
Protein Similarity:
100
95.8
66.3
96.3
N.A.
95.9
45.5
N.A.
59.2
53.2
38.5
46
N.A.
47.9
N.A.
34.5
49
P-Site Identity:
100
100
6.6
93.3
N.A.
86.6
6.6
N.A.
0
6.6
6.6
13.3
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
100
20
100
N.A.
86.6
60
N.A.
13.3
20
20
33.3
N.A.
40
N.A.
40
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
24
0
8
0
8
24
16
16
0
8
8
8
16
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
16
0
0
8
0
8
0
0
0
0
0
8
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
8
16
0
0
0
8
0
0
% F
% Gly:
8
24
0
0
0
0
0
8
0
0
8
16
8
0
8
% G
% His:
8
0
0
8
0
8
0
0
0
24
0
8
0
0
0
% H
% Ile:
0
0
31
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
0
8
8
16
0
0
8
0
0
0
8
0
31
0
% K
% Leu:
0
0
8
0
0
0
16
0
8
16
0
31
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
31
0
0
8
0
0
8
16
16
24
0
31
0
0
% N
% Pro:
0
8
0
0
0
8
0
0
0
8
0
0
24
8
8
% P
% Gln:
0
0
0
0
39
0
0
0
8
16
0
0
0
24
39
% Q
% Arg:
8
8
0
16
8
0
31
16
8
8
16
0
0
0
0
% R
% Ser:
8
24
24
16
8
47
39
39
31
0
39
0
16
16
8
% S
% Thr:
16
0
0
47
8
8
0
0
0
0
0
16
0
8
8
% T
% Val:
8
8
16
0
8
0
0
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _