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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD3
All Species:
19.39
Human Site:
S386
Identified Species:
35.56
UniProt:
A2A2Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A2Y4
NP_777598.3
597
68772
S386
P
L
Q
P
L
L
P
S
P
S
E
Q
E
E
E
Chimpanzee
Pan troglodytes
XP_520094
581
66659
S370
P
L
Q
P
L
L
P
S
P
S
E
Q
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001102733
838
94037
S647
A
N
I
S
Q
S
R
S
S
H
S
L
N
K
Q
Dog
Lupus familis
XP_541268
582
66957
S372
P
L
Q
P
L
L
P
S
P
S
E
Q
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD4
595
68429
S386
P
L
Q
P
L
L
P
S
P
T
E
Q
E
E
E
Rat
Rattus norvegicus
Q5FVG2
731
81700
T486
P
D
D
V
N
V
A
T
M
S
H
E
L
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510887
421
48616
S238
D
S
L
G
P
I
I
S
S
S
P
T
K
D
H
Chicken
Gallus gallus
XP_413944
395
45595
C212
Y
G
V
D
P
H
P
C
K
D
V
S
G
N
A
Frog
Xenopus laevis
P11434
801
89411
P553
P
V
F
P
P
E
F
P
A
V
Q
R
K
T
P
Zebra Danio
Brachydanio rerio
O57457
619
70690
T382
T
S
E
G
Q
P
K
T
S
A
L
T
P
V
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609384
572
64686
P371
Q
I
R
Y
S
S
L
P
R
S
T
M
S
E
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
R708
T
I
R
P
N
V
Y
R
L
G
E
E
V
D
E
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
A369
Y
L
P
M
F
T
L
A
T
S
D
G
E
D
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
65.5
94.1
N.A.
91.2
29.1
N.A.
50.5
42.5
23.3
28.7
N.A.
30.1
N.A.
20.2
30.4
Protein Similarity:
100
95.8
66.3
96.3
N.A.
95.9
45.5
N.A.
59.2
53.2
38.5
46
N.A.
47.9
N.A.
34.5
49
P-Site Identity:
100
100
6.6
100
N.A.
93.3
26.6
N.A.
13.3
6.6
13.3
0
N.A.
13.3
N.A.
20
26.6
P-Site Similarity:
100
100
20
100
N.A.
100
46.6
N.A.
33.3
6.6
40
26.6
N.A.
26.6
N.A.
53.3
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
8
8
8
8
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
0
0
0
0
0
8
8
0
0
24
0
% D
% Glu:
0
0
8
0
0
8
0
0
0
0
39
16
39
47
54
% E
% Phe:
0
0
8
0
8
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
16
0
0
0
0
0
8
0
8
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
8
8
0
0
0
8
% H
% Ile:
0
16
8
0
0
8
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
8
0
8
0
0
0
16
8
8
% K
% Leu:
0
39
8
0
31
31
16
0
8
0
8
8
8
0
0
% L
% Met:
0
0
0
8
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
8
0
0
16
0
0
0
0
0
0
0
8
8
0
% N
% Pro:
47
0
8
47
24
8
39
16
31
0
8
0
8
0
16
% P
% Gln:
8
0
31
0
16
0
0
0
0
0
8
31
0
0
8
% Q
% Arg:
0
0
16
0
0
0
8
8
8
0
0
8
0
0
0
% R
% Ser:
0
16
0
8
8
16
0
47
24
54
8
8
8
0
0
% S
% Thr:
16
0
0
0
0
8
0
16
8
8
8
16
0
8
0
% T
% Val:
0
8
8
8
0
16
0
0
0
8
8
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
16
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _