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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD3
All Species:
7.88
Human Site:
T235
Identified Species:
14.44
UniProt:
A2A2Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A2Y4
NP_777598.3
597
68772
T235
K
D
S
T
G
T
T
T
F
L
G
F
T
A
A
Chimpanzee
Pan troglodytes
XP_520094
581
66659
G233
A
G
F
V
V
F
Q
G
N
K
R
I
H
L
I
Rhesus Macaque
Macaca mulatta
XP_001102733
838
94037
T517
K
D
S
T
G
T
T
T
F
L
G
F
T
A
A
Dog
Lupus familis
XP_541268
582
66957
V232
F
T
A
A
G
F
V
V
F
Q
G
N
K
R
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD4
595
68429
A235
K
D
S
R
G
A
T
A
F
L
G
F
T
A
A
Rat
Rattus norvegicus
Q5FVG2
731
81700
Y245
K
A
R
D
G
N
D
Y
S
L
G
L
T
P
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510887
421
48616
K108
I
F
P
K
Q
S
Q
K
L
E
R
K
I
V
E
Chicken
Gallus gallus
XP_413944
395
45595
M82
T
K
S
V
V
K
Q
M
R
A
Q
P
P
F
T
Frog
Xenopus laevis
P11434
801
89411
I394
K
D
L
E
G
V
D
I
K
L
G
V
C
S
G
Zebra Danio
Brachydanio rerio
O57457
619
70690
T237
V
V
V
Y
K
N
K
T
Q
V
G
K
Y
F
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609384
572
64686
R232
S
T
F
V
A
G
K
R
S
Q
H
F
R
W
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
I236
V
D
A
N
H
L
P
I
E
I
G
V
G
A
V
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
S233
G
V
L
L
F
R
G
S
M
L
A
E
T
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
65.5
94.1
N.A.
91.2
29.1
N.A.
50.5
42.5
23.3
28.7
N.A.
30.1
N.A.
20.2
30.4
Protein Similarity:
100
95.8
66.3
96.3
N.A.
95.9
45.5
N.A.
59.2
53.2
38.5
46
N.A.
47.9
N.A.
34.5
49
P-Site Identity:
100
0
100
20
N.A.
80
33.3
N.A.
0
6.6
33.3
13.3
N.A.
6.6
N.A.
20
13.3
P-Site Similarity:
100
0
100
26.6
N.A.
80
33.3
N.A.
6.6
6.6
40
20
N.A.
6.6
N.A.
33.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
16
8
8
8
0
8
0
8
8
0
0
31
24
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
39
0
8
0
0
16
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
8
0
0
0
0
8
8
0
8
0
0
8
% E
% Phe:
8
8
16
0
8
16
0
0
31
0
0
31
0
24
0
% F
% Gly:
8
8
0
0
47
8
8
8
0
0
62
0
8
0
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
8
0
0
% H
% Ile:
8
0
0
0
0
0
0
16
0
8
0
8
8
0
16
% I
% Lys:
39
8
0
8
8
8
16
8
8
8
0
16
8
0
8
% K
% Leu:
0
0
16
8
0
8
0
0
8
47
0
8
0
8
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
16
0
0
8
0
0
8
0
0
8
% N
% Pro:
0
0
8
0
0
0
8
0
0
0
0
8
8
8
0
% P
% Gln:
0
0
0
0
8
0
24
0
8
16
8
0
0
0
0
% Q
% Arg:
0
0
8
8
0
8
0
8
8
0
16
0
8
8
0
% R
% Ser:
8
0
31
0
0
8
0
8
16
0
0
0
0
8
0
% S
% Thr:
8
16
0
16
0
16
24
24
0
0
0
0
39
0
16
% T
% Val:
16
16
8
24
16
8
8
8
0
8
0
16
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
8
% W
% Tyr:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _