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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD3
All Species:
10.61
Human Site:
T35
Identified Species:
19.44
UniProt:
A2A2Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A2Y4
NP_777598.3
597
68772
T35
L
S
Q
E
M
R
C
T
I
R
L
L
D
D
S
Chimpanzee
Pan troglodytes
XP_520094
581
66659
K37
C
H
I
Q
R
E
T
K
G
Q
F
L
I
D
H
Rhesus Macaque
Macaca mulatta
XP_001102733
838
94037
T317
L
S
Q
E
M
K
C
T
I
R
L
L
D
D
S
Dog
Lupus familis
XP_541268
582
66957
Q35
S
E
I
S
C
H
I
Q
R
E
T
K
G
Q
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD4
595
68429
T35
L
N
Q
E
M
K
C
T
I
R
L
L
D
D
S
Rat
Rattus norvegicus
Q5FVG2
731
81700
R46
A
K
S
V
I
T
C
R
V
S
L
L
D
G
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510887
421
48616
Chicken
Gallus gallus
XP_413944
395
45595
Frog
Xenopus laevis
P11434
801
89411
C195
R
R
S
P
N
M
R
C
K
V
T
L
L
D
D
Zebra Danio
Brachydanio rerio
O57457
619
70690
S35
Q
Q
Q
G
I
K
K
S
T
R
G
S
V
V
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609384
572
64686
G35
E
F
Q
P
F
H
K
G
I
Y
L
L
E
Y
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
F35
Q
I
R
C
T
V
T
F
L
D
S
T
S
Y
H
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
G36
E
F
Q
R
D
S
K
G
Q
F
L
L
D
Q
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
65.5
94.1
N.A.
91.2
29.1
N.A.
50.5
42.5
23.3
28.7
N.A.
30.1
N.A.
20.2
30.4
Protein Similarity:
100
95.8
66.3
96.3
N.A.
95.9
45.5
N.A.
59.2
53.2
38.5
46
N.A.
47.9
N.A.
34.5
49
P-Site Identity:
100
13.3
93.3
0
N.A.
86.6
26.6
N.A.
0
0
13.3
13.3
N.A.
26.6
N.A.
0
26.6
P-Site Similarity:
100
26.6
100
0
N.A.
100
46.6
N.A.
0
0
13.3
33.3
N.A.
33.3
N.A.
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% A
% Cys:
8
0
0
8
8
0
31
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
8
0
0
39
39
8
% D
% Glu:
16
8
0
24
0
8
0
0
0
8
0
0
8
0
0
% E
% Phe:
0
16
0
0
8
0
0
8
0
8
8
0
0
0
8
% F
% Gly:
0
0
0
8
0
0
0
16
8
0
8
0
8
8
0
% G
% His:
0
8
0
0
0
16
0
0
0
0
0
0
0
0
16
% H
% Ile:
0
8
16
0
16
0
8
0
31
0
0
0
8
0
0
% I
% Lys:
0
8
0
0
0
24
24
8
8
0
0
8
0
0
0
% K
% Leu:
24
0
0
0
0
0
0
0
8
0
47
62
8
0
16
% L
% Met:
0
0
0
0
24
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
16
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
16
8
47
8
0
0
0
8
8
8
0
0
0
16
0
% Q
% Arg:
8
8
8
8
8
8
8
8
8
31
0
0
0
0
0
% R
% Ser:
8
16
16
8
0
8
0
8
0
8
8
8
8
0
24
% S
% Thr:
0
0
0
0
8
8
16
24
8
0
16
8
0
0
8
% T
% Val:
0
0
0
8
0
8
0
0
8
8
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _