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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD3
All Species:
18.79
Human Site:
Y112
Identified Species:
34.44
UniProt:
A2A2Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A2Y4
NP_777598.3
597
68772
Y112
M
C
F
R
V
K
F
Y
P
H
E
P
L
K
I
Chimpanzee
Pan troglodytes
XP_520094
581
66659
L114
L
T
R
Y
L
L
Y
L
Q
I
K
R
D
I
F
Rhesus Macaque
Macaca mulatta
XP_001102733
838
94037
Y394
M
C
F
R
V
K
F
Y
P
H
E
P
L
K
I
Dog
Lupus familis
XP_541268
582
66957
Y112
I
K
E
E
L
T
R
Y
L
L
Y
L
Q
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD4
595
68429
Y112
M
C
F
R
V
K
F
Y
P
H
E
P
L
K
I
Rat
Rattus norvegicus
Q5FVG2
731
81700
Y123
L
H
L
R
V
K
F
Y
S
S
E
P
N
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510887
421
48616
Chicken
Gallus gallus
XP_413944
395
45595
Frog
Xenopus laevis
P11434
801
89411
Y272
F
T
S
N
V
K
F
Y
P
P
D
P
A
Q
L
Zebra Danio
Brachydanio rerio
O57457
619
70690
R112
K
L
K
E
E
I
T
R
Y
Q
F
F
L
Q
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609384
572
64686
L112
R
I
M
L
Y
Q
Q
L
K
R
D
L
R
H
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
Y112
L
F
F
R
V
K
F
Y
V
R
D
P
N
R
L
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
Q113
I
T
R
F
Q
L
F
Q
Q
L
K
R
D
L
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
65.5
94.1
N.A.
91.2
29.1
N.A.
50.5
42.5
23.3
28.7
N.A.
30.1
N.A.
20.2
30.4
Protein Similarity:
100
95.8
66.3
96.3
N.A.
95.9
45.5
N.A.
59.2
53.2
38.5
46
N.A.
47.9
N.A.
34.5
49
P-Site Identity:
100
0
100
6.6
N.A.
100
46.6
N.A.
0
0
40
6.6
N.A.
0
N.A.
46.6
6.6
P-Site Similarity:
100
26.6
100
20
N.A.
100
60
N.A.
0
0
60
20
N.A.
13.3
N.A.
73.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
24
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
24
0
16
0
0
% D
% Glu:
0
0
8
16
8
0
0
0
0
0
31
0
0
0
0
% E
% Phe:
8
8
31
8
0
0
54
0
0
0
8
8
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
24
0
0
0
8
0
% H
% Ile:
16
8
0
0
0
8
0
0
0
8
0
0
0
16
24
% I
% Lys:
8
8
8
0
0
47
0
0
8
0
16
0
0
24
8
% K
% Leu:
24
8
8
8
16
16
0
16
8
16
0
16
31
8
31
% L
% Met:
24
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
0
0
0
16
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
31
8
0
47
0
0
0
% P
% Gln:
0
0
0
0
8
8
8
8
16
8
0
0
8
16
0
% Q
% Arg:
8
0
16
39
0
0
8
8
0
16
0
16
8
8
0
% R
% Ser:
0
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% S
% Thr:
0
24
0
0
0
8
8
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
47
0
0
0
8
0
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
8
54
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _