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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD3
All Species:
17.27
Human Site:
Y310
Identified Species:
31.67
UniProt:
A2A2Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A2Y4
NP_777598.3
597
68772
Y310
E
N
Q
A
F
Y
K
Y
A
K
S
S
Q
I
K
Chimpanzee
Pan troglodytes
XP_520094
581
66659
Y294
E
N
Q
A
F
Y
K
Y
A
K
S
S
Q
I
K
Rhesus Macaque
Macaca mulatta
XP_001102733
838
94037
A574
A
F
H
T
S
T
P
A
A
C
K
H
L
W
K
Dog
Lupus familis
XP_541268
582
66957
Y296
E
N
Q
A
F
Y
K
Y
A
K
S
S
Q
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD4
595
68429
Y310
E
N
Q
A
F
Y
K
Y
A
K
S
S
Q
I
K
Rat
Rattus norvegicus
Q5FVG2
731
81700
R344
G
F
I
R
L
G
S
R
F
R
Y
S
G
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510887
421
48616
N165
F
R
P
P
E
S
L
N
P
V
T
G
S
R
K
Chicken
Gallus gallus
XP_413944
395
45595
Y139
D
A
A
L
L
A
A
Y
I
L
Q
A
E
I
G
Frog
Xenopus laevis
P11434
801
89411
F469
V
C
V
E
H
H
T
F
F
R
L
T
S
T
E
Zebra Danio
Brachydanio rerio
O57457
619
70690
T306
E
N
E
S
N
S
L
T
R
K
L
S
K
F
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609384
572
64686
L295
E
Q
M
L
F
F
T
L
P
N
S
Q
S
A
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
F310
C
C
I
E
Q
H
T
F
F
R
L
K
T
P
P
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
G293
E
N
Q
G
F
Y
H
G
T
T
Q
K
E
A
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
65.5
94.1
N.A.
91.2
29.1
N.A.
50.5
42.5
23.3
28.7
N.A.
30.1
N.A.
20.2
30.4
Protein Similarity:
100
95.8
66.3
96.3
N.A.
95.9
45.5
N.A.
59.2
53.2
38.5
46
N.A.
47.9
N.A.
34.5
49
P-Site Identity:
100
100
13.3
100
N.A.
100
6.6
N.A.
6.6
13.3
0
26.6
N.A.
20
N.A.
0
33.3
P-Site Similarity:
100
100
13.3
100
N.A.
100
13.3
N.A.
13.3
33.3
33.3
46.6
N.A.
26.6
N.A.
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
31
0
8
8
8
39
0
0
8
0
16
8
% A
% Cys:
8
16
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
54
0
8
16
8
0
0
0
0
0
0
0
16
0
8
% E
% Phe:
8
16
0
0
47
8
0
16
24
0
0
0
0
8
0
% F
% Gly:
8
0
0
8
0
8
0
8
0
0
0
8
8
0
8
% G
% His:
0
0
8
0
8
16
8
0
0
0
0
8
0
0
0
% H
% Ile:
0
0
16
0
0
0
0
0
8
0
0
0
0
39
0
% I
% Lys:
0
0
0
0
0
0
31
0
0
39
8
16
8
8
47
% K
% Leu:
0
0
0
16
16
0
16
8
0
8
24
0
8
0
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
47
0
0
8
0
0
8
0
8
0
0
0
0
0
% N
% Pro:
0
0
8
8
0
0
8
0
16
0
0
0
0
8
8
% P
% Gln:
0
8
39
0
8
0
0
0
0
0
16
8
31
0
0
% Q
% Arg:
0
8
0
8
0
0
0
8
8
24
0
0
0
8
0
% R
% Ser:
0
0
0
8
8
16
8
0
0
0
39
47
24
0
8
% S
% Thr:
0
0
0
8
0
8
24
8
8
8
8
8
8
8
8
% T
% Val:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% W
% Tyr:
0
0
0
0
0
39
0
39
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _