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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD3
All Species:
23.94
Human Site:
Y333
Identified Species:
43.89
UniProt:
A2A2Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A2Y4
NP_777598.3
597
68772
Y333
F
K
G
S
R
F
R
Y
S
G
K
V
A
K
E
Chimpanzee
Pan troglodytes
XP_520094
581
66659
Y317
F
K
G
S
R
F
R
Y
S
G
K
V
A
K
E
Rhesus Macaque
Macaca mulatta
XP_001102733
838
94037
Q597
Y
K
Y
A
K
S
S
Q
I
K
T
V
S
S
S
Dog
Lupus familis
XP_541268
582
66957
Y319
F
K
G
S
R
F
R
Y
S
G
K
V
A
K
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD4
595
68429
Y333
F
K
G
S
R
F
R
Y
S
G
K
V
A
K
E
Rat
Rattus norvegicus
Q5FVG2
731
81700
F367
K
A
R
R
S
T
S
F
E
R
R
P
S
K
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510887
421
48616
I188
M
V
K
C
L
V
K
I
Q
T
R
R
S
L
H
Chicken
Gallus gallus
XP_413944
395
45595
Q162
E
G
Y
S
S
K
F
Q
F
F
P
K
H
S
E
Frog
Xenopus laevis
P11434
801
89411
Y492
S
L
G
S
T
F
R
Y
S
G
R
T
Q
A
Q
Zebra Danio
Brachydanio rerio
O57457
619
70690
I329
S
G
K
T
A
M
Q
I
G
R
E
S
T
E
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609384
572
64686
Y318
S
W
G
T
K
F
R
Y
T
G
R
T
E
R
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
Y333
N
F
G
S
K
F
R
Y
S
G
R
T
E
Y
Q
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
S316
K
E
P
T
V
A
R
S
P
P
L
I
R
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
65.5
94.1
N.A.
91.2
29.1
N.A.
50.5
42.5
23.3
28.7
N.A.
30.1
N.A.
20.2
30.4
Protein Similarity:
100
95.8
66.3
96.3
N.A.
95.9
45.5
N.A.
59.2
53.2
38.5
46
N.A.
47.9
N.A.
34.5
49
P-Site Identity:
100
100
13.3
100
N.A.
100
6.6
N.A.
0
13.3
46.6
0
N.A.
40
N.A.
46.6
6.6
P-Site Similarity:
100
100
40
100
N.A.
100
26.6
N.A.
20
13.3
60
26.6
N.A.
73.3
N.A.
66.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
8
0
0
0
0
0
0
31
8
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
8
8
0
0
0
0
0
0
8
0
8
0
16
8
47
% E
% Phe:
31
8
0
0
0
54
8
8
8
8
0
0
0
0
0
% F
% Gly:
0
16
54
0
0
0
0
0
8
54
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% H
% Ile:
0
0
0
0
0
0
0
16
8
0
0
8
0
0
0
% I
% Lys:
16
39
16
0
24
8
8
0
0
8
31
8
0
39
0
% K
% Leu:
0
8
0
0
8
0
0
0
0
0
8
0
0
8
0
% L
% Met:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
8
0
0
0
0
0
8
8
8
8
0
8
0
% P
% Gln:
0
0
0
0
0
0
8
16
8
0
0
0
8
0
16
% Q
% Arg:
0
0
8
8
31
0
62
0
0
16
39
8
8
8
16
% R
% Ser:
24
0
0
54
16
8
16
8
47
0
0
8
24
16
8
% S
% Thr:
0
0
0
24
8
8
0
0
8
8
8
24
8
0
8
% T
% Val:
0
8
0
0
8
8
0
0
0
0
0
39
0
0
0
% V
% Trp:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
16
0
0
0
0
54
0
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _