KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD3
All Species:
15.76
Human Site:
Y512
Identified Species:
28.89
UniProt:
A2A2Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A2Y4
NP_777598.3
597
68772
Y512
R
R
A
L
S
W
S
Y
D
I
L
T
G
H
I
Chimpanzee
Pan troglodytes
XP_520094
581
66659
Y496
R
R
A
L
S
W
S
Y
D
I
L
T
G
H
I
Rhesus Macaque
Macaca mulatta
XP_001102733
838
94037
L755
L
F
D
C
P
S
R
L
E
L
E
R
E
D
T
Dog
Lupus familis
XP_541268
582
66957
Y497
H
Q
A
L
S
W
S
Y
D
I
L
S
G
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD4
595
68429
Y510
R
Q
A
L
S
W
S
Y
S
I
L
T
G
H
I
Rat
Rattus norvegicus
Q5FVG2
731
81700
L637
T
D
E
L
D
A
L
L
L
S
L
T
E
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510887
421
48616
N346
L
V
G
N
I
Q
V
N
E
F
V
R
S
F
S
Chicken
Gallus gallus
XP_413944
395
45595
S320
K
G
S
R
F
R
Y
S
G
R
V
A
K
E
V
Frog
Xenopus laevis
P11434
801
89411
G684
T
I
S
N
A
T
N
G
E
K
G
E
I
P
T
Zebra Danio
Brachydanio rerio
O57457
619
70690
N498
R
N
R
S
R
Q
S
N
E
M
V
D
S
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609384
572
64686
A488
A
V
N
S
S
S
P
A
D
S
F
L
H
A
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
Y894
K
Q
T
T
N
C
C
Y
R
E
F
S
I
R
D
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
L480
S
L
I
L
L
I
L
L
I
L
I
T
S
V
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
65.5
94.1
N.A.
91.2
29.1
N.A.
50.5
42.5
23.3
28.7
N.A.
30.1
N.A.
20.2
30.4
Protein Similarity:
100
95.8
66.3
96.3
N.A.
95.9
45.5
N.A.
59.2
53.2
38.5
46
N.A.
47.9
N.A.
34.5
49
P-Site Identity:
100
100
0
80
N.A.
86.6
20
N.A.
0
0
0
13.3
N.A.
13.3
N.A.
6.6
13.3
P-Site Similarity:
100
100
13.3
93.3
N.A.
93.3
33.3
N.A.
13.3
26.6
26.6
33.3
N.A.
13.3
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
31
0
8
8
0
8
0
0
0
8
0
16
0
% A
% Cys:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
8
0
0
0
31
0
0
8
0
8
16
% D
% Glu:
0
0
8
0
0
0
0
0
31
8
8
8
16
8
0
% E
% Phe:
0
8
0
0
8
0
0
0
0
8
16
0
0
8
0
% F
% Gly:
0
8
8
0
0
0
0
8
8
0
8
0
31
0
0
% G
% His:
8
0
0
0
0
0
0
0
0
0
0
0
8
31
0
% H
% Ile:
0
8
8
0
8
8
0
0
8
31
8
0
16
0
31
% I
% Lys:
16
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% K
% Leu:
16
8
0
47
8
0
16
24
8
16
39
8
0
0
16
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
8
16
8
0
8
16
0
0
0
0
0
8
0
% N
% Pro:
0
0
0
0
8
0
8
0
0
0
0
0
0
8
8
% P
% Gln:
0
24
0
0
0
16
0
0
0
0
0
0
0
0
0
% Q
% Arg:
31
16
8
8
8
8
8
0
8
8
0
16
0
8
0
% R
% Ser:
8
0
16
16
39
16
39
8
8
16
0
16
24
0
8
% S
% Thr:
16
0
8
8
0
8
0
0
0
0
0
39
0
0
16
% T
% Val:
0
16
0
0
0
0
8
0
0
0
24
0
0
8
8
% V
% Trp:
0
0
0
0
0
31
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _