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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FRMD3
All Species:
9.09
Human Site:
Y77
Identified Species:
16.67
UniProt:
A2A2Y4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A2Y4
NP_777598.3
597
68772
Y77
K
D
Y
F
G
I
R
Y
V
D
P
E
K
Q
R
Chimpanzee
Pan troglodytes
XP_520094
581
66659
K79
E
P
N
K
S
I
F
K
Q
M
K
S
K
P
G
Rhesus Macaque
Macaca mulatta
XP_001102733
838
94037
Y359
K
D
Y
F
G
I
R
Y
V
D
P
E
K
Q
R
Dog
Lupus familis
XP_541268
582
66957
K77
R
H
W
L
E
P
N
K
S
I
S
K
Q
M
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8BHD4
595
68429
Y77
K
D
Y
F
G
I
R
Y
V
D
P
E
K
Q
R
Rat
Rattus norvegicus
Q5FVG2
731
81700
F88
S
D
Y
F
G
L
R
F
M
D
S
A
Q
V
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510887
421
48616
Chicken
Gallus gallus
XP_413944
395
45595
Frog
Xenopus laevis
P11434
801
89411
A237
E
E
D
Y
F
G
L
A
I
W
E
S
P
T
C
Zebra Danio
Brachydanio rerio
O57457
619
70690
L77
W
L
D
P
S
K
T
L
A
E
H
K
D
L
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609384
572
64686
Q77
L
S
K
S
I
I
K
Q
C
K
E
M
D
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
V77
F
G
L
V
F
I
A
V
D
N
S
S
A
Q
Q
Sea Urchin
Strong. purpuratus
XP_784053
556
63534
Q78
C
K
K
N
A
L
K
Q
L
K
G
T
G
P
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.9
65.5
94.1
N.A.
91.2
29.1
N.A.
50.5
42.5
23.3
28.7
N.A.
30.1
N.A.
20.2
30.4
Protein Similarity:
100
95.8
66.3
96.3
N.A.
95.9
45.5
N.A.
59.2
53.2
38.5
46
N.A.
47.9
N.A.
34.5
49
P-Site Identity:
100
13.3
100
0
N.A.
100
40
N.A.
0
0
0
0
N.A.
6.6
N.A.
13.3
0
P-Site Similarity:
100
20
100
33.3
N.A.
100
66.6
N.A.
0
0
26.6
13.3
N.A.
13.3
N.A.
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
8
8
8
0
0
8
8
0
8
% A
% Cys:
8
0
0
0
0
0
0
0
8
0
0
0
0
0
8
% C
% Asp:
0
31
16
0
0
0
0
0
8
31
0
0
16
0
0
% D
% Glu:
16
8
0
0
8
0
0
0
0
8
16
24
0
0
0
% E
% Phe:
8
0
0
31
16
0
8
8
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
31
8
0
0
0
0
8
0
8
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
8
47
0
0
8
8
0
0
0
0
8
% I
% Lys:
24
8
16
8
0
8
16
16
0
16
8
16
31
0
8
% K
% Leu:
8
8
8
8
0
16
8
8
8
0
0
0
0
8
8
% L
% Met:
0
0
0
0
0
0
0
0
8
8
0
8
0
8
0
% M
% Asn:
0
0
8
8
0
0
8
0
0
8
0
0
0
0
0
% N
% Pro:
0
8
0
8
0
8
0
0
0
0
24
0
8
24
8
% P
% Gln:
0
0
0
0
0
0
0
16
8
0
0
0
16
31
8
% Q
% Arg:
8
0
0
0
0
0
31
0
0
0
0
0
0
0
24
% R
% Ser:
8
8
0
8
16
0
0
0
8
0
24
24
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
0
% T
% Val:
0
0
0
8
0
0
0
8
24
0
0
0
0
8
0
% V
% Trp:
8
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
31
8
0
0
0
24
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _