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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPDC1
All Species:
13.64
Human Site:
S568
Identified Species:
37.5
UniProt:
A2A3K4
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A3K4
NP_689635.3
754
84457
S568
V
E
H
E
T
Q
D
S
K
D
L
S
E
A
A
Chimpanzee
Pan troglodytes
XP_001147844
754
84425
S568
V
A
H
E
T
Q
D
S
K
D
L
S
E
A
A
Rhesus Macaque
Macaca mulatta
XP_001104435
806
90439
S620
V
E
H
E
T
Q
D
S
K
D
L
A
E
A
A
Dog
Lupus familis
XP_533558
789
87654
D609
N
S
K
D
L
P
T
D
A
P
N
T
A
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q6NZK8
747
83916
L567
E
T
Q
D
S
T
D
L
S
E
A
V
P
H
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507604
808
91741
S612
V
G
C
E
S
Q
E
S
K
D
A
S
E
T
I
Chicken
Gallus gallus
XP_414322
781
88819
V606
S
E
A
I
P
H
I
V
L
Q
S
E
L
S
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L1R5
713
80277
S541
L
T
L
Q
S
E
L
S
P
E
T
R
H
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393922
636
72588
E478
A
W
Q
R
L
Q
M
E
T
D
L
D
I
L
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
88.8
74.4
N.A.
80.5
N.A.
N.A.
69.3
63.5
N.A.
50.9
N.A.
N.A.
28.1
N.A.
N.A.
Protein Similarity:
100
99.5
90.9
82.5
N.A.
87.8
N.A.
N.A.
79
75.8
N.A.
65.3
N.A.
N.A.
45
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
0
N.A.
13.3
N.A.
N.A.
53.3
6.6
N.A.
6.6
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
100
93.3
100
13.3
N.A.
33.3
N.A.
N.A.
66.6
13.3
N.A.
40
N.A.
N.A.
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
0
0
0
0
0
12
0
23
12
12
34
45
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
23
0
0
45
12
0
56
0
12
0
0
0
% D
% Glu:
12
34
0
45
0
12
12
12
0
23
0
12
45
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% F
% Gly:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
34
0
0
12
0
0
0
0
0
0
12
12
0
% H
% Ile:
0
0
0
12
0
0
12
0
0
0
0
0
12
0
12
% I
% Lys:
0
0
12
0
0
0
0
0
45
0
0
0
0
0
0
% K
% Leu:
12
0
12
0
23
0
12
12
12
0
45
0
12
34
12
% L
% Met:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% M
% Asn:
12
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% N
% Pro:
0
0
0
0
12
12
0
0
12
12
0
0
12
0
0
% P
% Gln:
0
0
23
12
0
56
0
0
0
12
0
0
0
0
12
% Q
% Arg:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% R
% Ser:
12
12
0
0
34
0
0
56
12
0
12
34
0
12
12
% S
% Thr:
0
23
0
0
34
12
12
0
12
0
12
12
0
12
0
% T
% Val:
45
0
0
0
0
0
0
12
0
0
0
12
0
0
0
% V
% Trp:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _