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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PIPSL
All Species:
2.42
Human Site:
S473
Identified Species:
5.93
UniProt:
A2A3N6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2A3N6
NP_003548
862
95048
S473
L
E
E
I
S
E
G
S
P
T
P
D
P
S
F
Chimpanzee
Pan troglodytes
NP_001131030
550
61213
R238
V
M
N
N
L
L
P
R
S
V
K
M
H
I
K
Rhesus Macaque
Macaca mulatta
NP_001130039
550
61219
R238
V
M
N
N
L
L
P
R
S
V
K
M
H
I
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P70182
546
60466
P234
V
V
M
N
N
L
L
P
R
S
V
K
M
H
M
Rat
Rattus norvegicus
Q5I6B8
688
75576
T376
E
A
I
E
T
D
D
T
M
G
G
I
P
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511349
767
84935
R454
S
S
P
S
K
R
G
R
S
A
L
L
A
V
K
Chicken
Gallus gallus
Q5ZJ58
540
60700
L228
S
N
P
T
F
K
D
L
D
F
L
Q
D
M
H
Frog
Xenopus laevis
NP_001083942
570
63296
T258
E
R
E
K
S
S
P
T
H
K
D
L
D
F
L
Zebra Danio
Brachydanio rerio
NP_001082822
584
64340
E272
M
P
E
G
I
Q
L
E
P
D
N
Y
N
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P55035
396
42600
I84
L
V
Q
P
K
G
E
I
N
L
L
T
G
I
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
56.3
55.9
N.A.
N.A.
52.7
45.8
N.A.
45.4
39.9
47.7
44.4
N.A.
20.7
N.A.
N.A.
N.A.
Protein Similarity:
100
57.8
57.5
N.A.
N.A.
56.1
56.8
N.A.
58.7
50.9
55
54.2
N.A.
31.6
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
N.A.
N.A.
0
6.6
N.A.
6.6
0
13.3
13.3
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
6.6
6.6
N.A.
N.A.
20
33.3
N.A.
6.6
6.6
20
33.3
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
10
0
0
10
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
10
20
0
10
10
10
10
20
0
0
% D
% Glu:
20
10
30
10
0
10
10
10
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
10
0
0
0
10
10
% F
% Gly:
0
0
0
10
0
10
20
0
0
10
10
0
10
0
0
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
20
10
10
% H
% Ile:
0
0
10
10
10
0
0
10
0
0
0
10
0
30
0
% I
% Lys:
0
0
0
10
20
10
0
0
0
10
20
10
0
0
30
% K
% Leu:
20
0
0
0
20
30
20
10
0
10
30
20
0
0
20
% L
% Met:
10
20
10
0
0
0
0
0
10
0
0
20
10
10
10
% M
% Asn:
0
10
20
30
10
0
0
0
10
0
10
0
10
0
0
% N
% Pro:
0
10
20
10
0
0
30
10
20
0
10
0
20
0
0
% P
% Gln:
0
0
10
0
0
10
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
10
0
0
0
10
0
30
10
0
0
0
0
0
10
% R
% Ser:
20
10
0
10
20
10
0
10
30
10
0
0
0
10
0
% S
% Thr:
0
0
0
10
10
0
0
20
0
10
0
10
0
0
0
% T
% Val:
30
20
0
0
0
0
0
0
0
20
10
0
0
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _