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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIPSL All Species: 0.91
Human Site: S822 Identified Species: 2.22
UniProt: A2A3N6 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A2A3N6 NP_003548 862 95048 S822 Q D P E F L Q S V L E N L P G
Chimpanzee Pan troglodytes NP_001131030 550 61213 P519 E G S P I P D P S F S P L V G
Rhesus Macaque Macaca mulatta NP_001130039 550 61219 P519 E G S P I P D P S F S P I V G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P70182 546 60466 P515 E G S P V P G P S F S P V V G
Rat Rattus norvegicus Q5I6B8 688 75576 P657 R R L R A V T P S H T G A P T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511349 767 84935 F736 L D H S P H L F Q A V D C Q E
Chicken Gallus gallus Q5ZJ58 540 60700 T509 K E L P S S S T F T L E D S A
Frog Xenopus laevis NP_001083942 570 63296 M539 P E I E L N M M R T E V L E E
Zebra Danio Brachydanio rerio NP_001082822 584 64340 L553 T E P D N S T L H S T G A E C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P55035 396 42600 G365 S V L E N L P G V D P Q S E A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.3 55.9 N.A. N.A. 52.7 45.8 N.A. 45.4 39.9 47.7 44.4 N.A. 20.7 N.A. N.A. N.A.
Protein Similarity: 100 57.8 57.5 N.A. N.A. 56.1 56.8 N.A. 58.7 50.9 55 54.2 N.A. 31.6 N.A. N.A. N.A.
P-Site Identity: 100 13.3 6.6 N.A. N.A. 6.6 6.6 N.A. 6.6 0 20 6.6 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 20 20 N.A. N.A. 20 20 N.A. 13.3 20 26.6 20 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 10 0 0 0 0 10 0 0 20 0 20 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % C
% Asp: 0 20 0 10 0 0 20 0 0 10 0 10 10 0 0 % D
% Glu: 30 30 0 30 0 0 0 0 0 0 20 10 0 30 20 % E
% Phe: 0 0 0 0 10 0 0 10 10 30 0 0 0 0 0 % F
% Gly: 0 30 0 0 0 0 10 10 0 0 0 20 0 0 40 % G
% His: 0 0 10 0 0 10 0 0 10 10 0 0 0 0 0 % H
% Ile: 0 0 10 0 20 0 0 0 0 0 0 0 10 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 10 0 30 0 10 20 10 10 0 10 10 0 30 0 0 % L
% Met: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 20 10 0 0 0 0 0 10 0 0 0 % N
% Pro: 10 0 20 40 10 30 10 40 0 0 10 30 0 20 0 % P
% Gln: 10 0 0 0 0 0 10 0 10 0 0 10 0 10 0 % Q
% Arg: 10 10 0 10 0 0 0 0 10 0 0 0 0 0 0 % R
% Ser: 10 0 30 10 10 20 10 10 40 10 30 0 10 10 0 % S
% Thr: 10 0 0 0 0 0 20 10 0 20 20 0 0 0 10 % T
% Val: 0 10 0 0 10 10 0 0 20 0 10 10 10 30 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _