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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PPIAL4A All Species: 15.45
Human Site: S21 Identified Species: 37.78
UniProt: A2BFH1 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A2BFH1 NP_001116540.1 164 18166 S21 G K P L G R I S I K Q F A D K
Chimpanzee Pan troglodytes XP_001164416 226 25019 S83 G K P L G R I S I K L F A D K
Rhesus Macaque Macaca mulatta XP_001086893 165 17874 S21 G E P L G R V S F E L F A D K
Dog Lupus familis XP_537928 164 17950 S21 R E P L G R V S F E L F A D K
Cat Felis silvestris
Mouse Mus musculus P17742 164 17953 S21 D E P L G R V S F E L F A D K
Rat Rattus norvegicus P10111 164 17856 C21 G E P L G R V C F E L F A D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25007 227 24648 V84 N E P L G R I V M E L R S D V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P52011 173 18532 V21 G K A S G R I V M E L Y D D V
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays P21569 172 18330 V21 G A P A G R I V M E L Y A N E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q42406 172 18360 E21 G T P I G R I E M E L F A D T
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 69 84.2 84.7 N.A. 82.3 82.3 N.A. N.A. N.A. N.A. N.A. N.A. 49.3 N.A. 61.8 N.A.
Protein Similarity: 100 70.3 88.4 88.4 N.A. 87.8 87.8 N.A. N.A. N.A. N.A. N.A. N.A. 57.7 N.A. 72.2 N.A.
P-Site Identity: 100 93.3 66.6 60 N.A. 60 60 N.A. N.A. N.A. N.A. N.A. N.A. 40 N.A. 40 N.A.
P-Site Similarity: 100 93.3 86.6 80 N.A. 80 80 N.A. N.A. N.A. N.A. N.A. N.A. 66.6 N.A. 60 N.A.
Percent
Protein Identity: N.A. 62.2 N.A. 63.3 N.A. N.A.
Protein Similarity: N.A. 73.8 N.A. 76.7 N.A. N.A.
P-Site Identity: N.A. 40 N.A. 53.3 N.A. N.A.
P-Site Similarity: N.A. 73.3 N.A. 73.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 10 10 0 0 0 0 0 0 0 0 80 0 0 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 10 90 0 % D
% Glu: 0 50 0 0 0 0 0 10 0 80 0 0 0 0 10 % E
% Phe: 0 0 0 0 0 0 0 0 40 0 0 70 0 0 0 % F
% Gly: 70 0 0 0 100 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 60 0 20 0 0 0 0 0 0 % I
% Lys: 0 30 0 0 0 0 0 0 0 20 0 0 0 0 60 % K
% Leu: 0 0 0 70 0 0 0 0 0 0 90 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 40 0 0 0 0 0 0 % M
% Asn: 10 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 0 90 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % Q
% Arg: 10 0 0 0 0 100 0 0 0 0 0 10 0 0 0 % R
% Ser: 0 0 0 10 0 0 0 50 0 0 0 0 10 0 0 % S
% Thr: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 0 0 0 40 30 0 0 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _