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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HFM1
All Species:
10.61
Human Site:
S1404
Identified Species:
21.21
UniProt:
A2PYH4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2PYH4
NP_001017975.3
1435
162610
S1404
V
D
F
F
I
R
N
S
E
C
K
K
E
V
D
Chimpanzee
Pan troglodytes
XP_524618
845
96632
E815
T
S
F
S
T
D
T
E
K
T
K
I
S
V
L
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537081
1567
175547
S1530
M
S
P
H
P
Q
P
S
C
S
F
I
I
Y
E
Cat
Felis silvestris
Mouse
Mus musculus
NP_808541
1434
161360
S1403
V
D
I
F
I
G
N
S
G
S
K
K
E
I
D
Rat
Rattus norvegicus
XP_002724973
1434
161022
S1403
V
D
I
F
I
G
N
S
D
S
K
K
E
I
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519189
952
107492
E923
C
N
F
L
D
D
T
E
S
T
E
T
S
A
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919555
1228
138324
R1199
S
T
D
R
T
G
L
R
S
D
F
P
D
V
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUV9
2142
244492
Q2090
I
K
R
L
T
L
Q
Q
K
A
K
V
K
L
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U2G0
2145
243812
E2088
I
K
R
L
V
I
N
E
K
S
S
V
Q
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298526
984
111701
Y955
E
R
Y
G
H
D
S
Y
K
L
M
T
P
K
H
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189410
1133
128271
E1104
K
R
S
D
T
S
L
E
Q
T
K
G
F
C
S
Baker's Yeast
Sacchar. cerevisiae
P51979
1187
135053
S1158
I
P
I
D
L
E
S
S
D
S
Y
S
S
N
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.8
N.A.
43.7
N.A.
76.8
76.4
N.A.
48.7
N.A.
N.A.
47.1
N.A.
22.4
N.A.
21.9
N.A.
Protein Similarity:
100
58.2
N.A.
56.4
N.A.
86.3
85.7
N.A.
56.6
N.A.
N.A.
63.2
N.A.
38
N.A.
37.8
N.A.
P-Site Identity:
100
20
N.A.
6.6
N.A.
66.6
66.6
N.A.
6.6
N.A.
N.A.
6.6
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
26.6
N.A.
26.6
N.A.
73.3
80
N.A.
20
N.A.
N.A.
13.3
N.A.
40
N.A.
46.6
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
24.6
26.6
N.A.
Protein Similarity:
40.8
N.A.
N.A.
41.6
43.6
N.A.
P-Site Identity:
0
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
20
N.A.
N.A.
13.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
9
% A
% Cys:
9
0
0
0
0
0
0
0
9
9
0
0
0
9
0
% C
% Asp:
0
25
9
17
9
25
0
0
17
9
0
0
9
0
42
% D
% Glu:
9
0
0
0
0
9
0
34
9
0
9
0
25
0
9
% E
% Phe:
0
0
25
25
0
0
0
0
0
0
17
0
9
0
0
% F
% Gly:
0
0
0
9
0
25
0
0
9
0
0
9
0
0
0
% G
% His:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
9
% H
% Ile:
25
0
25
0
25
9
0
0
0
0
0
17
9
17
0
% I
% Lys:
9
17
0
0
0
0
0
0
34
0
50
25
9
9
0
% K
% Leu:
0
0
0
25
9
9
17
0
0
9
0
0
0
17
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
9
0
0
0
0
34
0
0
0
0
0
0
9
0
% N
% Pro:
0
9
9
0
9
0
9
0
0
0
0
9
9
0
0
% P
% Gln:
0
0
0
0
0
9
9
9
9
0
0
0
9
0
0
% Q
% Arg:
0
17
17
9
0
9
0
9
0
0
0
0
0
0
0
% R
% Ser:
9
17
9
9
0
9
17
42
17
42
9
9
25
0
9
% S
% Thr:
9
9
0
0
34
0
17
0
0
25
0
17
0
0
17
% T
% Val:
25
0
0
0
9
0
0
0
0
0
0
17
0
25
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
9
0
0
9
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _