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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HFM1
All Species:
0.91
Human Site:
T441
Identified Species:
1.82
UniProt:
A2PYH4
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2PYH4
NP_001017975.3
1435
162610
T441
T
V
Q
S
V
S
Q
T
L
K
N
T
S
T
A
Chimpanzee
Pan troglodytes
XP_524618
845
96632
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537081
1567
175547
S460
K
G
E
S
W
K
C
S
N
S
K
Q
K
H
Q
Cat
Felis silvestris
Mouse
Mus musculus
NP_808541
1434
161360
R439
K
T
V
Q
S
L
S
R
D
L
E
S
A
S
P
Rat
Rattus norvegicus
XP_002724973
1434
161022
K439
K
T
V
Q
S
L
S
K
T
L
E
N
A
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519189
952
107492
R11
D
S
M
T
R
K
W
R
D
N
S
M
I
Q
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919555
1228
138324
H287
F
F
E
I
Q
D
A
H
L
I
F
T
T
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUV9
2142
244492
I636
E
A
L
V
A
R
T
I
R
N
I
E
T
T
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U2G0
2145
243812
I630
E
S
I
V
V
R
T
I
R
Q
M
E
Q
N
H
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298526
984
111701
M43
C
Y
H
S
D
V
N
M
V
I
S
A
P
T
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189410
1133
128271
N191
R
L
K
I
L
S
S
N
H
E
L
R
S
S
T
Baker's Yeast
Sacchar. cerevisiae
P51979
1187
135053
W245
I
I
T
T
P
E
K
W
D
L
L
T
R
R
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.8
N.A.
43.7
N.A.
76.8
76.4
N.A.
48.7
N.A.
N.A.
47.1
N.A.
22.4
N.A.
21.9
N.A.
Protein Similarity:
100
58.2
N.A.
56.4
N.A.
86.3
85.7
N.A.
56.6
N.A.
N.A.
63.2
N.A.
38
N.A.
37.8
N.A.
P-Site Identity:
100
0
N.A.
6.6
N.A.
0
0
N.A.
0
N.A.
N.A.
13.3
N.A.
6.6
N.A.
6.6
N.A.
P-Site Similarity:
100
0
N.A.
20
N.A.
20
13.3
N.A.
13.3
N.A.
N.A.
26.6
N.A.
13.3
N.A.
13.3
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
24.6
26.6
N.A.
Protein Similarity:
40.8
N.A.
N.A.
41.6
43.6
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
46.6
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
0
9
0
9
0
0
0
0
9
17
9
9
% A
% Cys:
9
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
0
9
9
0
0
25
0
0
0
0
0
0
% D
% Glu:
17
0
17
0
0
9
0
0
0
9
17
17
0
0
9
% E
% Phe:
9
9
0
0
0
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
9
0
0
0
0
9
9
0
0
0
0
9
9
% H
% Ile:
9
9
9
17
0
0
0
17
0
17
9
0
9
0
0
% I
% Lys:
25
0
9
0
0
17
9
9
0
9
9
0
9
0
0
% K
% Leu:
0
9
9
0
9
17
0
0
17
25
17
0
0
0
9
% L
% Met:
0
0
9
0
0
0
0
9
0
0
9
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
9
9
17
9
9
0
9
0
% N
% Pro:
0
0
0
0
9
0
0
0
0
0
0
0
9
0
17
% P
% Gln:
0
0
9
17
9
0
9
0
0
9
0
9
9
9
17
% Q
% Arg:
9
0
0
0
9
17
0
17
17
0
0
9
9
9
0
% R
% Ser:
0
17
0
25
17
17
25
9
0
9
17
9
17
25
0
% S
% Thr:
9
17
9
17
0
0
17
9
9
0
0
25
17
25
9
% T
% Val:
0
9
17
17
17
9
0
0
9
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
9
9
0
0
0
0
0
0
9
% W
% Tyr:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _