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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HFM1
All Species:
8.18
Human Site:
T505
Identified Species:
16.36
UniProt:
A2PYH4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2PYH4
NP_001017975.3
1435
162610
T505
F
P
C
S
S
N
Q
T
E
F
K
F
D
L
T
Chimpanzee
Pan troglodytes
XP_524618
845
96632
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537081
1567
175547
E531
K
F
R
S
I
F
K
E
F
P
Y
F
N
Y
I
Cat
Felis silvestris
Mouse
Mus musculus
NP_808541
1434
161360
T503
F
P
C
S
S
S
Q
T
E
F
K
F
D
L
A
Rat
Rattus norvegicus
XP_002724973
1434
161022
T503
F
P
S
S
S
N
Q
T
E
F
K
F
D
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519189
952
107492
I74
F
V
A
V
S
A
T
I
P
N
S
E
D
I
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919555
1228
138324
N350
H
F
Y
R
Q
A
I
N
P
E
S
K
A
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUV9
2142
244492
M704
A
L
K
R
F
Q
V
M
N
E
I
V
Y
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U2G0
2145
243812
M697
A
L
K
R
F
Q
A
M
N
E
V
V
Y
D
K
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298526
984
111701
E106
S
L
G
I
N
C
L
E
L
T
G
D
N
E
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189410
1133
128271
F254
Y
A
A
A
K
N
D
F
L
F
E
K
R
L
Q
Baker's Yeast
Sacchar. cerevisiae
P51979
1187
135053
E308
S
A
T
V
P
N
I
E
D
L
A
L
W
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.8
N.A.
43.7
N.A.
76.8
76.4
N.A.
48.7
N.A.
N.A.
47.1
N.A.
22.4
N.A.
21.9
N.A.
Protein Similarity:
100
58.2
N.A.
56.4
N.A.
86.3
85.7
N.A.
56.6
N.A.
N.A.
63.2
N.A.
38
N.A.
37.8
N.A.
P-Site Identity:
100
0
N.A.
13.3
N.A.
86.6
86.6
N.A.
20
N.A.
N.A.
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
0
N.A.
26.6
N.A.
93.3
86.6
N.A.
26.6
N.A.
N.A.
0
N.A.
0
N.A.
0
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
24.6
26.6
N.A.
Protein Similarity:
40.8
N.A.
N.A.
41.6
43.6
N.A.
P-Site Identity:
0
N.A.
N.A.
20
13.3
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
17
17
9
0
17
9
0
0
0
9
0
9
0
25
% A
% Cys:
0
0
17
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
0
9
0
0
9
34
9
0
% D
% Glu:
0
0
0
0
0
0
0
25
25
25
9
9
0
17
0
% E
% Phe:
34
17
0
0
17
9
0
9
9
34
0
34
0
0
9
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
9
0
17
9
0
0
9
0
0
9
9
% I
% Lys:
9
0
17
0
9
0
9
0
0
0
25
17
0
0
25
% K
% Leu:
0
25
0
0
0
0
9
0
17
9
0
9
0
42
0
% L
% Met:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
34
0
9
17
9
0
0
17
0
0
% N
% Pro:
0
25
0
0
9
0
0
0
17
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
9
17
25
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
9
25
0
0
0
0
0
0
0
0
9
0
0
% R
% Ser:
17
0
9
34
34
9
0
0
0
0
17
0
0
9
0
% S
% Thr:
0
0
9
0
0
0
9
25
0
9
0
0
0
0
9
% T
% Val:
0
9
0
17
0
0
9
0
0
0
9
17
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% W
% Tyr:
9
0
9
0
0
0
0
0
0
0
9
0
17
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _