KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HFM1
All Species:
9.39
Human Site:
T556
Identified Species:
18.79
UniProt:
A2PYH4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2PYH4
NP_001017975.3
1435
162610
T556
K
D
A
K
F
I
M
T
V
E
Q
K
Q
R
L
Chimpanzee
Pan troglodytes
XP_524618
845
96632
D17
A
L
C
S
Q
R
F
D
D
W
K
E
K
F
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537081
1567
175547
W582
L
M
E
V
P
L
P
W
S
N
I
K
I
V
Y
Cat
Felis silvestris
Mouse
Mus musculus
NP_808541
1434
161360
S554
K
D
A
K
F
I
I
S
V
E
Q
K
L
R
L
Rat
Rattus norvegicus
XP_002724973
1434
161022
T554
K
D
A
K
F
I
I
T
V
E
Q
K
L
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519189
952
107492
L125
K
T
E
F
K
F
D
L
M
L
N
Y
K
I
A
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919555
1228
138324
V401
P
V
K
L
R
K
V
V
L
G
F
P
C
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUV9
2142
244492
G755
L
G
S
F
L
K
E
G
S
A
S
M
E
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U2G0
2145
243812
G748
L
S
A
F
M
R
E
G
S
A
S
T
E
I
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298526
984
111701
D157
D
I
G
L
L
L
I
D
E
V
H
L
L
N
D
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189410
1133
128271
N305
A
M
T
Y
G
Y
S
N
P
F
I
K
S
R
E
Baker's Yeast
Sacchar. cerevisiae
P51979
1187
135053
S359
Q
K
D
A
I
Y
N
S
K
L
I
E
I
I
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.8
N.A.
43.7
N.A.
76.8
76.4
N.A.
48.7
N.A.
N.A.
47.1
N.A.
22.4
N.A.
21.9
N.A.
Protein Similarity:
100
58.2
N.A.
56.4
N.A.
86.3
85.7
N.A.
56.6
N.A.
N.A.
63.2
N.A.
38
N.A.
37.8
N.A.
P-Site Identity:
100
0
N.A.
6.6
N.A.
80
86.6
N.A.
6.6
N.A.
N.A.
0
N.A.
6.6
N.A.
13.3
N.A.
P-Site Similarity:
100
20
N.A.
13.3
N.A.
93.3
93.3
N.A.
20
N.A.
N.A.
13.3
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
24.6
26.6
N.A.
Protein Similarity:
40.8
N.A.
N.A.
41.6
43.6
N.A.
P-Site Identity:
0
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
0
34
9
0
0
0
0
0
17
0
0
0
0
9
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
9
25
9
0
0
0
9
17
9
0
0
0
0
0
9
% D
% Glu:
0
0
17
0
0
0
17
0
9
25
0
17
17
0
17
% E
% Phe:
0
0
0
25
25
9
9
0
0
9
9
0
0
9
0
% F
% Gly:
0
9
9
0
9
0
0
17
0
9
0
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
9
0
0
9
25
25
0
0
0
25
0
17
25
0
% I
% Lys:
34
9
9
25
9
17
0
0
9
0
9
42
17
0
0
% K
% Leu:
25
9
0
17
17
17
0
9
9
17
0
9
25
0
42
% L
% Met:
0
17
0
0
9
0
9
0
9
0
0
9
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
9
0
9
9
0
0
9
0
% N
% Pro:
9
0
0
0
9
0
9
0
9
0
0
9
0
0
0
% P
% Gln:
9
0
0
0
9
0
0
0
0
0
25
0
9
0
0
% Q
% Arg:
0
0
0
0
9
17
0
0
0
0
0
0
0
34
0
% R
% Ser:
0
9
9
9
0
0
9
17
25
0
17
0
9
0
9
% S
% Thr:
0
9
9
0
0
0
0
17
0
0
0
9
0
0
0
% T
% Val:
0
9
0
9
0
0
9
9
25
9
0
0
0
17
0
% V
% Trp:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
17
0
0
0
0
0
9
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _