KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HFM1
All Species:
13.33
Human Site:
Y678
Identified Species:
26.67
UniProt:
A2PYH4
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2PYH4
NP_001017975.3
1435
162610
Y678
R
L
S
T
R
D
K
Y
I
Q
M
L
A
C
R
Chimpanzee
Pan troglodytes
XP_524618
845
96632
E137
P
N
A
E
D
I
A
E
W
L
S
D
G
E
R
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537081
1567
175547
Q780
V
I
R
T
Y
S
D
Q
K
P
T
L
V
F
D
Cat
Felis silvestris
Mouse
Mus musculus
NP_808541
1434
161360
Y676
R
L
S
T
R
E
K
Y
V
Q
M
L
A
C
N
Rat
Rattus norvegicus
XP_002724973
1434
161022
Y676
R
L
S
T
R
E
K
Y
V
Q
M
L
A
C
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519189
952
107492
S245
A
H
L
V
V
I
K
S
T
M
H
Y
V
G
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001919555
1228
138324
T521
P
V
L
F
T
T
S
T
L
A
M
G
V
N
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUV9
2142
244492
Y879
N
H
S
E
L
Q
F
Y
L
S
L
L
N
Q
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9U2G0
2145
243812
Y872
N
H
S
E
L
Q
Y
Y
L
S
L
M
N
Q
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002298526
984
111701
Q277
S
C
S
D
K
Q
L
Q
S
Y
I
L
Y
G
G
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_189410
1133
128271
M425
D
T
G
M
V
I
I
M
T
R
R
E
T
V
H
Baker's Yeast
Sacchar. cerevisiae
P51979
1187
135053
Q479
S
W
N
S
S
E
I
Q
E
Y
S
D
L
D
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
57.8
N.A.
43.7
N.A.
76.8
76.4
N.A.
48.7
N.A.
N.A.
47.1
N.A.
22.4
N.A.
21.9
N.A.
Protein Similarity:
100
58.2
N.A.
56.4
N.A.
86.3
85.7
N.A.
56.6
N.A.
N.A.
63.2
N.A.
38
N.A.
37.8
N.A.
P-Site Identity:
100
6.6
N.A.
13.3
N.A.
80
80
N.A.
6.6
N.A.
N.A.
6.6
N.A.
20
N.A.
13.3
N.A.
P-Site Similarity:
100
13.3
N.A.
20
N.A.
93.3
93.3
N.A.
6.6
N.A.
N.A.
20
N.A.
40
N.A.
40
N.A.
Percent
Protein Identity:
25.7
N.A.
N.A.
24.6
26.6
N.A.
Protein Similarity:
40.8
N.A.
N.A.
41.6
43.6
N.A.
P-Site Identity:
13.3
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
9
0
0
9
0
0
25
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
25
0
% C
% Asp:
9
0
0
9
9
9
9
0
0
0
0
17
0
9
9
% D
% Glu:
0
0
0
25
0
25
0
9
9
0
0
9
0
9
0
% E
% Phe:
0
0
0
9
0
0
9
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
9
9
17
17
% G
% His:
0
25
0
0
0
0
0
0
0
0
9
0
0
0
9
% H
% Ile:
0
9
0
0
0
25
17
0
9
0
9
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
34
0
9
0
0
0
0
0
0
% K
% Leu:
0
25
17
0
17
0
9
0
25
9
17
50
9
0
0
% L
% Met:
0
0
0
9
0
0
0
9
0
9
34
9
0
0
9
% M
% Asn:
17
9
9
0
0
0
0
0
0
0
0
0
17
9
17
% N
% Pro:
17
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
25
0
25
0
25
0
0
0
17
17
% Q
% Arg:
25
0
9
0
25
0
0
0
0
9
9
0
0
0
17
% R
% Ser:
17
0
50
9
9
9
9
9
9
17
17
0
0
0
0
% S
% Thr:
0
9
0
34
9
9
0
9
17
0
9
0
9
0
0
% T
% Val:
9
9
0
9
17
0
0
0
17
0
0
0
25
9
9
% V
% Trp:
0
9
0
0
0
0
0
0
9
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
9
42
0
17
0
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _