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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TARSL2
All Species:
17.88
Human Site:
T477
Identified Species:
28.1
UniProt:
A2RTX5
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2RTX5
NP_689547.2
802
92646
T477
H
Y
S
E
N
M
F
T
F
E
I
E
K
D
T
Chimpanzee
Pan troglodytes
XP_001144545
802
92628
T477
H
Y
S
E
N
M
F
T
F
E
I
E
K
D
T
Rhesus Macaque
Macaca mulatta
XP_001086926
670
78232
F379
C
P
G
H
C
L
M
F
A
H
R
P
R
S
W
Dog
Lupus familis
XP_536172
802
92150
T477
H
Y
S
E
N
M
F
T
F
D
I
E
K
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLY2
790
91300
T465
H
Y
S
N
N
M
F
T
F
D
V
E
K
D
T
Rat
Rattus norvegicus
Q5XHY5
695
80557
L404
R
S
W
R
E
L
P
L
R
L
A
D
F
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513531
677
78488
I386
R
S
W
R
E
M
P
I
R
L
A
D
F
G
V
Chicken
Gallus gallus
XP_413774
903
103081
S578
H
Y
S
E
N
M
F
S
F
E
I
E
K
E
T
Frog
Xenopus laevis
NP_001087812
721
82862
C415
P
M
N
C
P
G
H
C
L
M
F
D
H
R
P
Zebra Danio
Brachydanio rerio
NP_001116258
718
82843
D416
P
G
H
C
L
M
F
D
H
R
P
R
S
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_723726
690
79327
E398
N
R
N
R
S
W
R
E
L
P
L
R
M
A
D
Honey Bee
Apis mellifera
XP_395662
714
83384
N416
C
M
I
F
D
V
R
N
R
S
W
R
E
L
P
Nematode Worm
Caenorhab. elegans
P52709
725
84399
C416
P
M
N
C
P
G
H
C
L
M
F
G
H
M
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O04630
709
80918
Q415
P
G
H
C
L
I
F
Q
H
R
V
R
S
Y
R
Baker's Yeast
Sacchar. cerevisiae
P04801
734
84502
K416
E
K
E
T
F
G
L
K
P
M
N
C
P
G
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
75
88.5
N.A.
85.9
65.3
N.A.
73.4
67.1
65.3
65.8
N.A.
59.4
58.4
53.3
N.A.
Protein Similarity:
100
99.7
78.4
94.1
N.A.
91.5
75.6
N.A.
79
75.1
76.8
77.3
N.A.
70.8
71.9
69
N.A.
P-Site Identity:
100
100
0
93.3
N.A.
80
0
N.A.
6.6
86.6
0
13.3
N.A.
0
0
0
N.A.
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
13.3
N.A.
13.3
100
13.3
13.3
N.A.
26.6
20
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
47.3
49.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62
66.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
7
0
14
0
0
7
0
% A
% Cys:
14
0
0
27
7
0
0
14
0
0
0
7
0
0
0
% C
% Asp:
0
0
0
0
7
0
0
7
0
14
0
20
0
27
7
% D
% Glu:
7
0
7
27
14
0
0
7
0
20
0
34
7
7
0
% E
% Phe:
0
0
0
7
7
0
47
7
34
0
14
0
14
0
0
% F
% Gly:
0
14
7
0
0
20
0
0
0
0
0
7
0
20
0
% G
% His:
34
0
14
7
0
0
14
0
14
7
0
0
14
0
7
% H
% Ile:
0
0
7
0
0
7
0
7
0
0
27
0
0
0
0
% I
% Lys:
0
7
0
0
0
0
0
7
0
0
0
0
34
0
0
% K
% Leu:
0
0
0
0
14
14
7
7
20
14
7
0
0
7
0
% L
% Met:
0
20
0
0
0
47
7
0
0
20
0
0
7
7
0
% M
% Asn:
7
0
20
7
34
0
0
7
0
0
7
0
0
0
0
% N
% Pro:
27
7
0
0
14
0
14
0
7
7
7
7
7
0
20
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
14
7
0
20
0
0
14
0
20
14
7
27
7
7
14
% R
% Ser:
0
14
34
0
7
0
0
7
0
7
0
0
14
7
0
% S
% Thr:
0
0
0
7
0
0
0
27
0
0
0
0
0
0
34
% T
% Val:
0
0
0
0
0
7
0
0
0
0
14
0
0
0
14
% V
% Trp:
0
0
14
0
0
7
0
0
0
0
7
0
0
7
7
% W
% Tyr:
0
34
0
0
0
0
0
0
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _