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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TARSL2 All Species: 8.79
Human Site: Y457 Identified Species: 13.81
UniProt: A2RTX5 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A2RTX5 NP_689547.2 802 92646 Y457 E V L S P N M Y N S K L W E A
Chimpanzee Pan troglodytes XP_001144545 802 92628 Y457 E V L S P N M Y N S K L W E A
Rhesus Macaque Macaca mulatta XP_001086926 670 78232 E359 S E N M F T F E I E K D T F A
Dog Lupus familis XP_536172 802 92150 F457 E V L S P N M F N S K L W E T
Cat Felis silvestris
Mouse Mus musculus Q8BLY2 790 91300 Y445 E V L S P N M Y N S K L W E T
Rat Rattus norvegicus Q5XHY5 695 80557 N384 Q F A L K P M N C P G H C L M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513531 677 78488 N366 T F A L K P M N C P G H C L M
Chicken Gallus gallus XP_413774 903 103081 F558 E V V S P N I F N S K L W E T
Frog Xenopus laevis NP_001087812 721 82862 F395 Q H Y S E N M F S F E V E K E
Zebra Danio Brachydanio rerio NP_001116258 718 82843 V396 E N M F S F E V E K E I F A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_723726 690 79327 K378 E K E K F A L K P M N C P G H
Honey Bee Apis mellifera XP_395662 714 83384 E396 F S F D V E K E T F A L K P M
Nematode Worm Caenorhab. elegans P52709 725 84399 F396 Q H Y S E D M F K I E V E K E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O04630 709 80918 I395 D N M F T F N I E K Q E F G L
Baker's Yeast Sacchar. cerevisiae P04801 734 84502 W396 L W E T S G H W A N Y K E N M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.2 75 88.5 N.A. 85.9 65.3 N.A. 73.4 67.1 65.3 65.8 N.A. 59.4 58.4 53.3 N.A.
Protein Similarity: 100 99.7 78.4 94.1 N.A. 91.5 75.6 N.A. 79 75.1 76.8 77.3 N.A. 70.8 71.9 69 N.A.
P-Site Identity: 100 100 13.3 86.6 N.A. 93.3 6.6 N.A. 6.6 73.3 20 6.6 N.A. 6.6 6.6 13.3 N.A.
P-Site Similarity: 100 100 13.3 93.3 N.A. 93.3 13.3 N.A. 6.6 93.3 60 33.3 N.A. 13.3 6.6 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. 47.3 49.8 N.A.
Protein Similarity: N.A. N.A. N.A. 62 66.5 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 0 0 7 0 0 7 0 7 0 0 7 20 % A
% Cys: 0 0 0 0 0 0 0 0 14 0 0 7 14 0 0 % C
% Asp: 7 0 0 7 0 7 0 0 0 0 0 7 0 0 0 % D
% Glu: 47 7 14 0 14 7 7 14 14 7 20 7 20 34 14 % E
% Phe: 7 14 7 14 14 14 7 27 0 14 0 0 14 7 0 % F
% Gly: 0 0 0 0 0 7 0 0 0 0 14 0 0 14 0 % G
% His: 0 14 0 0 0 0 7 0 0 0 0 14 0 0 7 % H
% Ile: 0 0 0 0 0 0 7 7 7 7 0 7 0 0 0 % I
% Lys: 0 7 0 7 14 0 7 7 7 14 40 7 7 14 0 % K
% Leu: 7 0 27 14 0 0 7 0 0 0 0 40 0 14 14 % L
% Met: 0 0 14 7 0 0 54 0 0 7 0 0 0 0 27 % M
% Asn: 0 14 7 0 0 40 7 14 34 7 7 0 0 7 0 % N
% Pro: 0 0 0 0 34 14 0 0 7 14 0 0 7 7 0 % P
% Gln: 20 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 7 7 0 47 14 0 0 0 7 34 0 0 0 0 0 % S
% Thr: 7 0 0 7 7 7 0 0 7 0 0 0 7 0 20 % T
% Val: 0 34 7 0 7 0 0 7 0 0 0 14 0 0 0 % V
% Trp: 0 7 0 0 0 0 0 7 0 0 0 0 34 0 0 % W
% Tyr: 0 0 14 0 0 0 0 20 0 0 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _