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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AGPHD1
All Species:
10.91
Human Site:
Y189
Identified Species:
21.82
UniProt:
A2RU49
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2RU49
NP_001013641.2
373
41933
Y189
P
L
L
E
K
Y
L
Y
A
L
G
Q
N
R
N
Chimpanzee
Pan troglodytes
XP_001151085
373
41867
Y189
P
L
L
E
K
Y
L
Y
A
L
G
Q
N
R
N
Rhesus Macaque
Macaca mulatta
XP_001107962
373
42049
Y189
P
L
L
E
K
Y
L
Y
V
L
G
Q
N
R
N
Dog
Lupus familis
XP_532363
376
41415
D192
P
L
L
E
K
H
V
D
I
L
G
Q
G
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q5U5V2
376
42338
G192
P
L
L
E
K
Y
M
G
A
L
S
Q
S
R
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513213
377
42528
H193
P
L
L
E
K
Y
V
H
A
L
D
G
N
G
N
Chicken
Gallus gallus
XP_413743
377
41399
D192
P
L
L
E
Q
Y
V
D
A
L
G
Q
N
E
Y
Frog
Xenopus laevis
Q6PB06
374
42244
H191
S
L
L
R
K
Y
A
H
A
V
K
E
T
E
L
Zebra Danio
Brachydanio rerio
A8WFT6
355
40467
H178
P
L
L
N
Q
Y
V
H
V
M
D
G
D
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_724122
417
47466
Y238
P
E
L
R
Q
F
L
Y
V
V
K
D
Q
E
Q
Honey Bee
Apis mellifera
XP_001121301
361
41891
H195
P
Q
L
H
Q
F
I
H
A
I
K
N
V
F
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788471
385
44058
Q196
P
R
L
R
N
H
L
Q
V
L
K
E
D
S
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
95.7
74.7
N.A.
79.5
N.A.
N.A.
67.1
59.1
51.8
46.6
N.A.
29.7
33.5
N.A.
31.4
Protein Similarity:
100
99.7
98.1
87.2
N.A.
89.3
N.A.
N.A.
82.2
72.6
70.8
66.7
N.A.
49.4
53.3
N.A.
53.2
P-Site Identity:
100
100
93.3
60
N.A.
73.3
N.A.
N.A.
66.6
66.6
33.3
26.6
N.A.
26.6
20
N.A.
26.6
P-Site Similarity:
100
100
93.3
80
N.A.
86.6
N.A.
N.A.
80
80
53.3
60
N.A.
46.6
53.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
9
0
59
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
17
0
0
17
9
17
0
0
% D
% Glu:
0
9
0
59
0
0
0
0
0
0
0
17
0
25
9
% E
% Phe:
0
0
0
0
0
17
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
0
9
0
0
42
17
9
9
0
% G
% His:
0
0
0
9
0
17
0
34
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
9
0
9
9
0
0
0
0
0
% I
% Lys:
0
0
0
0
59
0
0
0
0
0
34
0
0
0
0
% K
% Leu:
0
75
100
0
0
0
42
0
0
67
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
9
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
9
9
0
0
0
0
0
0
9
42
0
50
% N
% Pro:
92
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
9
0
0
34
0
0
9
0
0
0
50
9
9
17
% Q
% Arg:
0
9
0
25
0
0
0
0
0
0
0
0
0
34
0
% R
% Ser:
9
0
0
0
0
0
0
0
0
0
9
0
9
9
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% T
% Val:
0
0
0
0
0
0
34
0
34
17
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
67
0
34
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _