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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HMX2 All Species: 23.33
Human Site: S130 Identified Species: 46.67
UniProt: A2RU54 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens A2RU54 NP_005510.1 273 29598 S130 L L P A G S P S P G S E R P R
Chimpanzee Pan troglodytes XP_508091 273 29596 S130 L L P A G S P S P G S E R P R
Rhesus Macaque Macaca mulatta XP_001105231 273 29541 S130 L L P A G S P S P G S E R P R
Dog Lupus familis XP_544055 273 29473 S130 L L P A G S P S P G P E R P R
Cat Felis silvestris
Mouse Mus musculus P43687 273 29616 S130 L L P A G S P S P G P E R P R
Rat Rattus norvegicus P63156 327 35117 D151 S V S S A S S D S E Y K V K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517986 237 25439 A99 P D A A S Q R A S G R K K K T
Chicken Gallus gallus O57601 308 33768 S153 A E I V L E E S D S E E G K K
Frog Xenopus laevis Q8JJ64 306 34004 S112 S L L L G P T S P V S G G E R
Zebra Danio Brachydanio rerio Q504H8 297 33069 A124 V L K S D P D A K D D E D D N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VEI9 592 62591 T399 Q H P H Q P T T P T S S S S S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus Q26656 405 44721 S226 K D S R G R E S P D S E H R R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.8 94.8 N.A. 93.7 28.4 N.A. 39.1 37.9 37.5 37 N.A. 24.6 N.A. N.A. 29.1
Protein Similarity: 100 99.6 97.8 95.2 N.A. 94.8 39.1 N.A. 51.2 53.5 50 50.8 N.A. 32 N.A. N.A. 40.7
P-Site Identity: 100 100 100 93.3 N.A. 93.3 6.6 N.A. 13.3 13.3 40 13.3 N.A. 20 N.A. N.A. 40
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 26.6 N.A. 33.3 20 40 33.3 N.A. 26.6 N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 50 9 0 0 17 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 17 0 0 9 0 9 9 9 17 9 0 9 9 0 % D
% Glu: 0 9 0 0 0 9 17 0 0 9 9 67 0 9 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 59 0 0 0 0 50 0 9 17 0 0 % G
% His: 0 9 0 9 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 9 0 0 0 0 0 9 0 0 17 9 25 9 % K
% Leu: 42 59 9 9 9 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 9 0 50 0 0 25 42 0 67 0 17 0 0 42 0 % P
% Gln: 9 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 9 0 9 9 0 0 0 9 0 42 9 59 % R
% Ser: 17 0 17 17 9 50 9 67 17 9 50 9 9 9 9 % S
% Thr: 0 0 0 0 0 0 17 9 0 9 0 0 0 0 9 % T
% Val: 9 9 0 9 0 0 0 0 0 9 0 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _