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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HMX2
All Species:
19.7
Human Site:
S260
Identified Species:
39.39
UniProt:
A2RU54
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A2RU54
NP_005510.1
273
29598
S260
Y
Y
P
G
S
N
L
S
A
L
P
L
Y
N
L
Chimpanzee
Pan troglodytes
XP_508091
273
29596
S260
Y
Y
P
G
S
N
L
S
A
L
P
L
Y
N
L
Rhesus Macaque
Macaca mulatta
XP_001105231
273
29541
S260
Y
Y
P
G
S
N
L
S
A
L
P
L
Y
N
L
Dog
Lupus familis
XP_544055
273
29473
S260
Y
Y
P
G
S
N
L
S
A
L
P
L
Y
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P43687
273
29616
S260
Y
Y
P
S
S
N
L
S
A
L
P
L
Y
N
L
Rat
Rattus norvegicus
P63156
327
35117
A289
G
P
S
A
P
P
P
A
L
Q
R
P
L
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517986
237
25439
A225
P
L
P
T
F
P
S
A
M
P
F
L
R
P
Q
Chicken
Gallus gallus
O57601
308
33768
V292
L
L
T
F
P
H
P
V
Y
Y
S
H
P
S
V
Frog
Xenopus laevis
Q8JJ64
306
34004
P289
P
L
L
T
F
P
H
P
V
Y
Y
S
H
P
V
Zebra Danio
Brachydanio rerio
Q504H8
297
33069
V281
L
L
T
F
P
H
P
V
Y
Y
S
H
P
I
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VEI9
592
62591
R579
M
Q
Y
Y
A
A
A
R
N
T
S
P
P
R
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Q26656
405
44721
S364
E
N
H
P
T
T
G
S
S
L
H
S
P
N
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.8
94.8
N.A.
93.7
28.4
N.A.
39.1
37.9
37.5
37
N.A.
24.6
N.A.
N.A.
29.1
Protein Similarity:
100
99.6
97.8
95.2
N.A.
94.8
39.1
N.A.
51.2
53.5
50
50.8
N.A.
32
N.A.
N.A.
40.7
P-Site Identity:
100
100
100
100
N.A.
93.3
0
N.A.
13.3
0
0
0
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
6.6
N.A.
20
20
13.3
13.3
N.A.
6.6
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
9
9
9
17
42
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
17
17
0
0
0
0
0
9
0
0
0
0
% F
% Gly:
9
0
0
34
0
0
9
0
0
0
0
0
0
0
0
% G
% His:
0
0
9
0
0
17
9
0
0
0
9
17
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
17
34
9
0
0
0
42
0
9
50
0
50
9
0
42
% L
% Met:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
0
9
0
0
0
42
0
0
9
0
0
0
0
50
0
% N
% Pro:
17
9
50
9
25
25
25
9
0
9
42
17
34
17
17
% P
% Gln:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
9
0
9
9
0
% R
% Ser:
0
0
9
9
42
0
9
50
9
0
25
17
0
9
0
% S
% Thr:
0
0
17
17
9
9
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
17
9
0
0
0
0
9
25
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
42
42
9
9
0
0
0
0
17
25
9
0
42
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _